Results 61 to 70 of about 2,408,039 (303)

A Centered Index of Spatial Concentration : Axiomatic Approach with an Application to Population and Capital Cities [PDF]

We construct an axiomatic index of spatial concentration around a center or capital point of interest, a concept with wide applicability from urban economics, economic geography and trade, to political economy and industrial organization.
Filipe R. Campante, Quoc-Anh Do
core   +7 more sources

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Modeling the Measurements of the Determinants of ICT Fluency and Evolution of Digital Divide Among Students in Developing Countries—East Africa Case Study

Applied Sciences, 2020
During the last decade, information and communication technology has brought remarkable changes to the education style of developed countries, especially in the context of online learning materials accessibility.
Jean-Pierre Niyigena, Qingshan Jiang, Djemel Ziou, Ruey-Shiang Shaw, A S M Touhidul Hasan   +4 more
doaj   +1 more source

Soluble ST2 levels and left ventricular structure and function in patients with metabolic syndrome [PDF]

, 2016
Background: A biomarker that is of great interest in relation to adverse cardiovascular events is soluble ST2 (sST2), a member of the interleukin family.
Beunza, Maite, Cardelli, Patrizia, Celic, Vera, Di Somma, Salvatore, Escribano, Elena, Floridi, Federico, Lopez-Andres, Natalia, Magrini, Laura, Majstorovic, Anka, Marino, Rossella, Melero, Amaia, Pencic-Popovic, Biljana, Roy, Ignacio, Salerno, Gerardo, Sljivic, Aleksandra   +14 more
core   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

A proof of concept on real-time air quality monitoring system [PDF]

, 2017
According to the Department of Environment Malaysia, Air Pollutant Index (API) is an indicator for the air quality status at any particular area. API is calculated based on average concentration of air pollutants such as Sulphur Dioxide (SO2), Nitrogen ...
Ibrahim, Noraini, Saringat, Mohd Zainuri, Selvarajah, Ruban   +2 more
core  

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

FEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii, Edoardo Andrea Cutolo, Daniele Montepietra, Claudia Battarra, Roberto Caferri, Stefano Capaldi, Zeno Guardini, Luca Dall'Osto, Roberto Bassi   +8 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Spatial variability of concentration and aggressiveness of precipitation in North-East of Algeria

Journal of Water and Land Development, 2018
In this study, the spatial variation of daily and monthly concentration precipitation index and its aggressiveness were used in 23 rainfall stations in the extreme north-east of Algeria over the period 1970–2010.
Bessaklia Hanene, Ghenim Abderrahmane Nekkache, Megnounif Abdessalam, Martin-Vide Javier   +3 more
doaj   +1 more source