Results 71 to 80 of about 10,028,549 (330)

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

Modeling the economic and health impact of substandard uterotonics in Senegal

open access: yesBMC Pregnancy and Childbirth
Background Maternal mortality due to postpartum hemorrhage (PPH) remains a global concern especially in low- and lower-middle income countries. PPH is preventable with quality-assured uterotonics.
Yi-Fang Ashley Lee   +6 more
doaj   +1 more source

Eurobonds: The blue bond concept and its implications [PDF]

open access: yes
The Blue Bond proposal, published in May 2010 (Bruegel Policy Brief 2010/03) suggests that sovereign debt in euro-area countries be split into two parts. The first part, the senior â??Blueâ??
Jacques Delpla, Jakob von Weizsäcker
core   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Concept of Sub-Independence [PDF]

open access: yes, 2013
Limit theorems as well as other well-known results in probability and statistics are often based on the distributions of the sums of independent random variables.
Hamedani, Gholamhossein
core   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

Expansion of Tubular with Elastomers in Multilateral Wells

open access: yesThe Journal of Engineering Research, 2013
The use of solid expandable tubular technology during the last decade has focused on solving many challenges in well drilling and delivery including zonal isolation, deep drilling, conservation of hole sizes, etc.
Md Velden, FKS Al-Jahwari
doaj   +1 more source

Conservation : concept and reality. [PDF]

open access: yes, 2010
Before any individual, organisation or discipline contemplates its future, it is prudent to know where it currently stands, where it has come from and what the world around it is like.
Caple, C.
core   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

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