Results 91 to 100 of about 122,411 (287)

Myeloid‐Derived Grancalcin Promotes Periodontal Inflammation and Pathological Bone Remodeling in Periodontitis

open access: yesAdvanced Science, EarlyView.
Grancalcin (GCA), a myeloid‐derived protein, is enriched in gingival tissues of periodontitis patients and mouse models. Through interactions with CD44 and activation of MYH9, GCA promotes NF‐κB signaling and exacerbates periodontal inflammation and bone loss.
Min Zhou   +6 more
wiley   +1 more source

Pengembangan E-LKPD IPA Berbasis Concept Cartoons Terintegrasi Keterampilan Proses Sains untuk Siswa Kelas VIII

open access: yesResearch in Science and Mathematics Education
Tujuan - Penelitian ini bertujuan untuk menghasilkan e-LKPD IPA berbasis concept cartoon materi zat aditif dan adiktif yang layak digunakan dalam pembelajaran IPA serta teruji keterbacaan oleh peserta didik.
Seto Ari Wibowo   +2 more
doaj   +1 more source

Consistency between animation and 'real image' (registration based on photographic realism): resources present in Gumball’s graphic universe

open access: yesANIAV, 2018
The present article will focus on an example of hybrid animation, The Amazing World of Gumball (2011), which is a television animation series created by Ben Bocquelet (1983).
Manuela Elizabeth Rodríguez González
doaj   +1 more source

Computer-mediated collaboration and the transitioning of intercultural spaces [PDF]

open access: yes, 2010
The following implementation of computer-mediated collaboration\ud aims to help international students improve the quality of their intercultural experiences by applying strategies for synthesizing and applying knowledge obtained\ud through cross ...
McMichael, William
core  

Molecular Glue cc‐885 Inhibits VHL‐Deficient Clear Cell Renal Cell Carcinoma via ETS1 Degradation

open access: yesAdvanced Science, EarlyView.
VHL‐deficient kidney cancer lacks effective treatments. This study reveals that the molecular glue degrader cc‐885 hijacks the cellular recycling system to selectively destroy the oncogenic protein ETS1, effectively killing VHL‐mutant tumors. Combining CC‐885 with the approved drug belzutifan achieves powerful synergy, offering a promising new ...
Taowei Yang   +15 more
wiley   +1 more source

The Effectiveness of Concept Cartoons to Enhance Conceptual Understanding of Kinematic Concepts

open access: yesJurnal Pembelajaran Fisika, 2019
Understanding kinematic concepts is essential for students to develop a strong foundation in physics and to appreciate the basic principles of nature. This study aims to investigate the effectiveness of concept cartoons in enhancing the conceptual understanding of kinematic concepts among students. This research is an experimental study using a pretest-
openaire   +1 more source

Modelling Discourse-related terminology in OntoLingAnnot’s ontologies [PDF]

open access: yes, 2010
Recently, computational linguists have shown great interest in discourse annotation in an attempt to capture the internal relations in texts. With this aim, we have formalized the linguistic knowledge associated to discourse into different linguistic ...
Aguado de Cea, G., Pareja-Lora, A.
core   +1 more source

An Implantable Scaffold Sequentially Releasing STING Agonist and B7‐H3 Antibody for Bone Metastasis Immunotherapy

open access: yesAdvanced Science, EarlyView.
We developed an implantable dual‐drug depot using GelMA for bone metastasis treatment, co‐delivering MSA‐2 and αB7‐H3‐loaded CaCO3 microparticles. Sustained release from GelMA scaffold enables MSA‐2 to activate STING signaling and enhance T‐cell infiltration and activation, while sequentially released αB7‐H3 blocks MSA‐2‐induced B7‐H3 upregulation ...
Qijun Lin   +10 more
wiley   +1 more source

Learning to teach ideas and evidence in science: a study of school mentors and trainee teachers [PDF]

open access: yes, 2006
This article reports on a small-scale evaluation of how beginning teachers undertaking a PGCE in secondary science worked collaboratively with their school based mentors to enhance practice in the use of ideas and evidence in science.
Maloney, Jane, Simon, Shirley
core   +1 more source

Postsynaptic Complexin Mediates Constitutive Exocytosis of Nicotinic Acetylcholine Receptor

open access: yesAdvanced Science, EarlyView.
Beyond its established presynaptic role, complexin is identified as a postsynaptic regulator of neurotransmitter receptor trafficking. By promoting constitutive and activity‐dependent exocytosis of nicotinic acetylcholine receptors, complexin controls spontaneous synaptic signaling at the C.
Ya Wang   +4 more
wiley   +1 more source

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