Results 131 to 140 of about 15,736 (254)
Movement Disorders, EarlyView.Abstract Background SRRM4 is an exclusively neural‐expressed splicing‐factor gene not yet associated with a monogenic condition. Objective We sought to delineate movement disorders caused by SRRM4 variants. De novo splice‐donor‐site variants at position +2 of intron 5 of SRRM4 (c.464+2T>C, c.464+2T>A) occurred in three unrelated patients with dystonia ...
Philip Harrer +24 more
wiley +1 more source
Relationship Between Qualitative Differences in Discourse Impairment and Theory of Mind in Patients With Right Hemisphere Damage: A Case Series. [PDF]
CureusHoyano K, Kobayashi Y.
europepmc +1 more source
Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
Medicinal Research Reviews, EarlyView.ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source
A study on the mechanism of Buyang Huanwu Decoction in treating epilepsy by regulating adenosine levels. [PDF]
Sci RepWu S, Deng Y, Yang J, Peng Z, Chen J.
europepmc +1 more source
Nonpharmacologic Therapy for Pediatric Posttonsillectomy Pain: A Systematic Review
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective To understand efficacies of nonpharmacologic therapy for pediatric posttonsillectomy pain. Data Sources CINAHL, Cochrane Library, PubMed, and Scopus. Review Methods Studies on nonpharmacologic interventions for pediatric posttonsillectomy pain were included in this systematic review.
Justina T. Sargios +5 more
wiley +1 more source
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT The role of the cell envelope‐associated Rv0132c/FGD2 from Mycobacterium tuberculosis has long been a subject of debate. Importantly, FGD2 is found only in pathogenic mycobacteria, making it a potential drug target. While some suggest it functions as a glucose‐6‐phosphate dehydrogenase, others propose it acts instead as an F420‐dependent ...
Adewale V. Aderemi +12 more
wiley +1 more source
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT Proteins are built from modular domains that serve as fundamental units of structure and evolution. While individual domains have been extensively cataloged, their collective distribution across the lineages of life has remained poorly resolved.
Rui Guo +5 more
wiley +1 more source
On Churchill's black dog, Barzun's bicycle, and cartoon bears: living within the bipolar temperament. [PDF]
Int J Bipolar DisordD' Agati DV, D' Agati DC.
europepmc +1 more source
Fluorinated Amphiphilic Dendrimer to Improve PET Imaging of Cancer
Small, EarlyView.Fluorination of a self‐assembling dendrimer nanosystem reduced liver retention, accelerated renal clearance and improved biodistribution, ultimately enhancing tumor uptake and enabling more sensitive tumor detection by positron emission tomography (PET).
Béatrice Louis +16 more
wiley +1 more source
Reconfigurable Nanogap SERS for Multiscale Molecular Sensing on Curved Surfaces
Small, EarlyView.Reconfigurable Au‐coated SMP nanocomposites enable adaptive SERS through reversible tuning of Au─Au nanogaps. Embedded AgNPs serve as photothermal triggers and reinforcements. Wide gaps facilitate macromolecule detection, while narrowed gaps enhance small‐molecule signals for reliable multiscale sensing on curved surfaces.
Goum Min +13 more
wiley +1 more source