Results 121 to 130 of about 122,411 (287)

Novel Monoclonal Antibody Detects Small Aβ Oligomers More Sensitively Than Lecanemab in Alzheimer's Disease CSF, Serum and Culture Media

Annals of Neurology, EarlyView.
Objective Aqueously diffusible oligomers of the amyloid β‐protein (oAβ) are neurotoxic and play a role in neuronal dysfunction in Alzheimer's disease (AD). Accurate quantification of oAβ in brains and biofluids could be valuable for understanding and monitoring AD.
Yi Ran Xu, Youqi Tao, Alexandra M. Lish, Shaomin Li, Beth L. Ostaszewski, Amirah K. Anderson, Tracy Young‐Pearse, Trebor L. Lawton, Hyun‐Sik Yang, Dominic M. Walsh, Ting Yang, Dennis J. Selkoe   +11 more
wiley   +1 more source

Prediction-Observation-Explanation (POE) Method and Its Efficiency in Teaching “Work, Energy, Power” Concepts

International Journal of Assessment Tools in Education, 2020
With the developing technology educating students free from misconceptions, making sense of their learnings and using them in daily life are primarily aimed.
Sevilay Karamustafaoğlu, Turgay Nalkıran   +1 more
doaj  

PROMOTING ECONOMIC LITERACY: IDEAS FOR YOUR CLASSROOM [PDF]

Instructors hope their students retain an understanding of course material beyond the end of the term; in agricultural economics courses, improved retention may take the form of increased economic literacy. This paper offers practical ideas for improving
Mathews, Leah Greden
core   +1 more source

Epiléptico: la ascensión del Gran Mal. Un acercamiento a la autoficción a través de la novela gráfica europea

Impossibilia: Revista Internacional de Estudios Literarios, 2017
Resumen: En este artículo realizamos un análisis de los componentes autoficcionales de la novela gráfica Epiléptico: la ascensión del Gran Mal, de David B. (2001-2007).
Alberto Escalante Varona, Jorge Juan Carrillo Santos   +1 more
doaj  

Nano‐Gs Protein Peptidomimetics: Rational Design of Gα C‐Terminus‐Derived Peptides Mimicking Key Components of Gs‐β2AR Interactions

Angewandte Chemie International Edition, EarlyView.
G protein‐coupled receptors (GPCRs) are major therapeutic targets. Modulating GPCR activity through intracellular sites is evolving. A structure‐ and computation‐assisted approach generated small G protein‐derived peptidomimetics targeting the intracellular binding crevice of the β2 adrenergic receptor mimicking features of the full G protein.
Phuong Thu Tran, Mia Danielsen, Johanna K. S. Tiemann, Passainte Ibrahim, Søren G. F. Rasmussen, Xavier Kubiak, Hossein Batebi, Charlène Gadais, Steven Ballet, Peter W. Hildebrand, Daniel Sejer Pedersen, Jesper Mosolff Mathiesen   +11 more
wiley   +1 more source

Art+Politics

, 2011
For the exhibition Art + Politics, students worked closely with the holdings of Gettysburg College\u27s Special Collections and College Archives to curate an exhibition in Schmucker Art Gallery that engages with issues of public policy, activism, war ...
Adlon, Josiah B., Birkenshock, Jenna L., DeBiaso, Francesca S., Egan, Shannon, Francisco, Emily A., Glass, Shelby P., Goodall, Hillary B., Hilands, Megan E., Parrish, Colleen L., Reynolds, Molly E., Sheridan, Tessa M.   +10 more
core  

An elastic segment of the whisker shaft enables coding of the whisking phase via whisker torsion in rats and mice

The Anatomical Record, EarlyView.
An elastic segment was found in the basal part of the whisker shaft in rats and mice. Application of force to the whisker bulb of isolated follicles caused bending and twisting of this segment. Active whisker movements deform this segment, causing whisker shaft deflection and selective activation of mechanoreceptors at different phases of whisking ...
Sebastian Haidarliu, Guy Nelinger, Luka Gantar, Ehud Ahissar, Inbar Saraf‐Sinik   +4 more
wiley   +1 more source

Representation of Metaphor ‘FUTURE EVENTS ARE AHEAD’ in German Political Cartoons

RUDN Journal of Language Studies, Semiotics and Semantics
The paper studies the actualization of the metaphor ‘FUTURE EVENTS ARE AHEAD’ in the German political cartoon as a polycode text. The author of the article finds out that images and situations, which the cartoonist uses for the purpose of its ...
Galina L. Denisova
doaj   +1 more source

Autistic Children With Speech Onset Delay Show Reversed Bias in Spectral Versus Temporal Auditory Processing

Autism Research, EarlyView.
ABSTRACT A recent “hierarchical” reinterpretation of the neurological basis of autism suggests that in autism with early language delay, perceptual processing may be favored over the integration of transmodal information. This model is largely based on neuroimaging findings relating to visual processing, but predicts a corresponding reorganization in ...
Luodi Yu, Shuyu Xie, Li Wang, Laurent Mottron   +3 more
wiley   +1 more source

Event‐ and Time‐Based Prospective Memory and Time Perception in Autistic Adults With and Without Intellectual Disabilities

Autism Research, EarlyView.
ABSTRACT The aim of this study was to examine time perception (i.e., the sense of the duration, order and passage of time) and event‐ and time‐based prospective memory (PM; i.e., the ability to recall an intention to perform an action in the future) in adults across the wider autism spectrum including those with intellectual disabilities.
Daniela Nürnberg, Mareike Altgassen
wiley   +1 more source