Results 121 to 130 of about 22,041,249 (385)

The Revitalization Concept of “Pramuka Penggalang” in The Digital Game Design [PDF]

open access: yes, 2019
The scout activity is a non-formal education in environments such as school and family. Generally, it held in the outdoors as an attractive place, challenging, creative, innovative, and fun.
Budiman, A. (Arief)   +1 more
core  

The Concept, Design and Performance of a Novel Rotary Kiln Type Air-Staged Biomass Gasifier

open access: yes, 2016
Tar formation is the main bottleneck for biomass gasification technology. A novel rotary kiln type biomass gasification process was proposed. The concept design was based on air staging and process separation.
Hui-yuan Shi, Wenhua Si, Xi Li
semanticscholar   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

A new conceptual design method to support rapid and effective mapping from product design specification to concept design

open access: yes, 2016
Conceptual design has a decisive impact on the product development time, cost and success. This paper presents a new conceptual design method for achieving rapid and effective mapping from product design specification (PDS) to concept design. This method
Haizhu Zhang   +5 more
semanticscholar   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

An analysis of design reuse benefits [PDF]

open access: yes, 1998
Although the concept of design reuse is accepted as a valid approach to design, little attempt has been made to formalise the elements that constitutes design reuse. The few approaches formalising design reuse, e.g.
Duffy, A.H.B., Ferns, A. F.
core  

From sign to design: The role of domain transfer in redefining architecture locality

open access: yesARTEKS : Jurnal Teknik Arsitektur
This research examines the design process using conceptual frameworks based on domain transfer to suggest a new model for architecture based on local contexts.
Bramasta Putra Redyantanu   +1 more
doaj   +1 more source

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