Results 81 to 90 of about 22,041,249 (385)
Culture and concept design : a study of international teams [PDF]
, 2011 This paper explores the relationship between culture and performance in concept design. Economic globalisation has meant that the management of global teams has become of strategic importance in product development.
Grierson, Hilary +3 more
core
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Design Concept for a Failover Mechanism in Distributed SDN Controllers [PDF]
, 2017 Software defined networking allows the separation of the control plane and data plane in networking. It provides scalability, programmability, and centralized control. It will use these traits to reach ubiquitous connectivity.
Kong, Nathan
core +2 more sources
Refactorings of Design Defects using Relational Concept Analysis [PDF]
, 2008 Software engineers often need to identify and correct design defects, ıe} recurring design problems that hinder development and maintenance\ud by making programs harder to comprehend and--or evolve.
A.J. Riel +5 more
core +4 more sources
Aplikasi Nilai Objektivitas pada Konsep Desain Interior Kantor
Humaniora, 2013 Now days, planning an office was more than preparing desk and chair, it needed numbers of important decisions to be considerered, such as, where and how did the workers want to work?, What kinds of workspace that supported employee’s activities and how
Ulli Aulia Ruki
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Criticism and Function in Critical Design Practice [PDF]
, 2015 This article focuses on critical design as a field of industrial design practice. It considers some barriers and misconceptions to critical design practice being seen as part of a disciplinary project.
Malpass, Matt
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
A novel design concept for space-based polar remote sensing [PDF]
, 2012 Space-based remote sensing of the Earth is conducted from a fleet of spacecraft in two basic orbital positions, near-polar low-Earth orbits and geosynchronous orbits, with each offering its own advantages and disadvantages.
Anderson, Pamela +2 more
core
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source