Results 81 to 90 of about 1,419,473 (306)
Human–machine teaming for leisure motorboat layout design
Data-Centric EngineeringSpace utilization is a key driver for yacht design. Larger hulls increase the cost of the yacht substantially, and so space is always at a premium. The designs should feel spacious and luxurious, making the best use of the available volume while also ...
Thomas Savasta, Bill Edwards, Adam Sobey
doaj +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Optimization techniques with knowledge based control in ship concept design
, 1990 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.An integrated computational approach to Ship Concept Design using optimization techniques and a knowledge base to control the optimization process has been ...
Schachter, Richard David, Schachter, R.D
core
Integrated design at VIDA centre Poland [PDF]
, 2009 Organised by: Cranfield UniversityThe modern design process forces the tight integration of processes connected with the development of the product. All the steps of the design process are based on geometrical models created in CAD systems.
Konieczny, R. +4 more
core
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Design Interference Detector-A Tool for Predicting Intrinsic Design Failures [PDF]
, 2009 Organised by: Cranfield UniversityIntricate failures at the system integration phase of the design are mostly generated by interactions of product modules or/and engineering domains.
D’Amelio, V., Tomiyama, Tetsuo
core
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The Metreleptin Effectiveness and Safety Registry (MEASuRE): concept, design and challenges. [PDF]
Orphanet J Rare Dis, 2023 Haymond MW +8 more
europepmc +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source