Results 101 to 110 of about 544,256 (319)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Effects of stimuli organization on identity matching-to-sample performances of persons with autism / Desempenho de pessoas com autismo em tarefas de emparelhamento com o modelo por identidade: efeitos da organização dos estímulos

Psicologia: Reflexão e Crítica, 2008
This study assessed the performance of 20 persons with autism in an identity matching-to-sample task, using two procedures with different stimuli arrangements and different response requirements.
Camila Graciella Santos Gomes, Deisy das Graças de Souza   +1 more
doaj  

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

NEURONAL MECHANISMS OF MEMORY FORMATION: CONCEPTS OF LONG-TERM POTENTIATION AND BEYOND.: By Christian Holscher. 2001. Cambridge: Cambridge University Press. Price pound65. Pp. 528. ISBN 0-52177-067-X. [PDF]

, 2001
Zafar I. Bashir
openalex   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

A New Concept for the Formation of Homogeneous, Poly(ethylene oxide) based, Gel-Type Polymer Electrolyte [PDF]

, 2002
Yûichi Aihara, G. B. Appetecchi, Bruno Scrosati   +2 more
openalex   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

Formação de conceitos em crianças cegas: questões teóricas e implicações educacionais

Psicologia: Teoria e Pesquisa
A formação de conceitos depende da linguagem e do pensamento, que integram informações sensoriais. Postula-se que mudanças no sujeito que conhece e nos objetos e eventos a serem conhecidos sugerem modelos flexíveis de ensino de conceitos.
Cecilia Guarnieri Batista
doaj   +1 more source

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

Molecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo, Carlos M. Martínez‐Cáceres, Manuel Bernabé‐García, Vicente Munitiz, David Ruiz de Angulo, Pascual Parrilla, Ángeles Ortiz, Luisa F. Martínez de Haro, María L. Cayuela   +8 more
wiley   +1 more source

Desenvolvimento de conceitos: o paradigma das descobertas

Psicologia Escolar e Educacional
Keil investigou se a descoberta de essências internas ou princípios causais subjacentes alterariam as categorizações de crianças sobre conceitos de espécies naturais e artefatos. Esse trabalho replica parte do experimento de Keil (1989), buscando validar
José Fernando Bitencourt Lomônaco, Alessandra Gotuzo Seabra Capovilla, Carlos Eduardo Costa, Jussara Martins Albernaz, Marcia Azevedo De Souza, Ramatis Monteiro Aguiar   +5 more
doaj