Results 111 to 120 of about 11,719,816 (381)

Desenvolvimento de conceitos em cegos congênitos: caminhos de aquisição do conhecimento

open access: yesPsicologia Escolar e Educacional
O objetivo deste trabalho foi estudar o desenvolvimento de conceitos por cegos congênitos. Participaram sete cegos congênitos, de ambos os sexos, com idades entre 8 e 13 anos.
Sylvia da Silveira Nunes   +1 more
doaj  

Nursing diagnosis proposal "Impaired Peripheral Venous Return": concept formation. [PDF]

open access: yesRev Bras Enferm, 2023
Medeiros HPDS   +5 more
europepmc   +1 more source

Improving Bone Formation by Guided Bone Regeneration Using a Collagen Membrane with rhBMP-2: A Novel Concept [PDF]

open access: gold, 2023
Narae Jung   +8 more
openalex   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Design and Development of a Multifunctional Stepladder: Usability, Sustainability, and Cost-Effectiveness

open access: yesEng
This study presents the design, development, and evaluation of a multifunctional stepladder that integrates four functionalities: a stepladder, Pilates chair, wheelchair, and walking aid. Unlike existing research that focuses on single-function assistive
Elwin Nesan Selvanesan   +6 more
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

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