Results 131 to 140 of about 36,563 (251)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Attributed concept maps: fuzzy integration and fuzzy matching

open access: yes, 2011
[[abstract]]A concept map, typically depicted as a connected graph, is composed of a collection of propositions. Each proposition forming a semantic unit consists of a small set of concept nodes interconnected to one another with relation links.
Chang, K. E., Chen, S. W., Lin, S. C.
core  

Semi-automated map generation for concept gaming [PDF]

open access: yes, 2008
Conventional learning games have often limited flexibility to address individual needs of a learner. The concept gaming approach provides a frame for handling conceptual structures that are defined by a concept map.
Tarhio, Jorma, Lahti, Lauri
core  

Hierarchical Organization in Concept Maps as a path to explain the Elaboration of Knowledge in the History of Science

open access: yesScience Education International
An alternative to insert history of science (HS) in teacher formation programs is the use of concept maps (CM), which may be very useful to represent the historical elaboration dimension of science concepts, laws, and principles. This paper presents the
Paulo Victor Souza   +2 more
doaj  

The efficacy of provision of concept - maps preparation [PDF]

open access: yesفصلنامه نوآوری‌های آموزشی, 2008
Constructivism approach is one of the most important theoretical frameworks in the formation and development of the new instructional revisions and activities.
doaj  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Tundra bio-geo processes concept map

open access: yes, 2004
This website contains a concept map of the bio-geo processes in the Tundra. This concept map is part of a larger collection developed as course materials in Oklahoma State University's Introductory Biology course.
Anne Ewing
core  

Enhancing concept map teaching technology with student’s handwritten concept map notes

open access: yesThe Asia Pacific Scholar
Sulthan Al Rashid   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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