Results 81 to 90 of about 411,580 (297)
Aim: To evaluate the use of CMAP tools® software as a teaching strategy of skeletal muscle components and contraction in undergraduates students of physical education. Methods: Nineteen students from the discipline of fundamentals of human physiology of
Luis Carlos Jacinto +2 more
doaj +1 more source
Object-based learning with concept mapping embodied intelligent agent
For effective learning, the teaching materials for the learning purpose should be comprehensible and appropriate for the learners. Moreover, the learners are expected to construct the concepts and relations of the learning materials so as to achieve the ...
Depickere, A. +7 more
core
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
The use of professional knowledge (from different areas; content knowledge, pedagogical knowledge, pedagogical-psychological knowledge)—that is, scientific evidence in the broader sense—can help teachers to act professionally in complex pedagogical ...
Anna-Lena Molitor +2 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Although studies have identified numerous confusing concepts in high school biology, existing diagnostic and instructional methods remain inadequate.
Ruo-Wei Liu +4 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Acid-base physiology is widely recognized as one of the most conceptually challenging topics in undergraduate education due to its interdisciplinary nature and the necessity for both mechanistic and integrative understanding.
Tamara Dakic +5 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source

