Results 101 to 110 of about 2,934,510 (334)
COVIDBackground: Breakthrough infections (BTIs) continue to occur among healthcare workers (HCWs) despite full COVID-19 vaccination, raising concerns about ongoing vulnerability in this high-risk group.
Alfredo A. Hinay +3 more
doaj +1 more source
The Place of Immunotherapy in the Management of HCV-Induced Vasculitis: An Update
Clinical and Developmental Immunology, 2012 Patients with chronic hepatitis C virus (HCV) can develop systemic cryoglobulinemic vasculitis. Combination of pegylated-interferon α and ribavirin is the first-line treatment of this condition.
Laurent Chiche +3 more
doaj +1 more source
Glottodidactica, 2013 The present paper deals with both medium and conception of orality and literality on text level, and aims at giving an outline of some important aspects underlying the discussion about the differences between written and spoken language and their impact ...
Iwona Machowicz
doaj +1 more source
Epistemological Tensions in Bourdieu's Conception of Social Science [PDF]
, 2011 The main purpose of this paper is to explore Pierre Bourdieu’s conception of social science. To this end, the paper sheds light on the main epistemological presuppositions that undergird Bourdieu’s defence of reflexive sociology as a scientific endeavour.
Susen, S.
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Predicting the toxicity-efficacy ratio of venetoclax in real-world patients
Annals of HematologyThis study investigates the pharmacokinetic variability and exposure-response relationships of Venetoclax (VEN) in adult patients with acute myeloid leukemia (AML) who are ineligible for intensive chemotherapy.
Loïc Osanno +16 more
doaj +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Revista Brasileira de Educação Especial, 2008 As concepções dos professores podem determinar as atitudes sociais em relação à inclusão do aluno com deficiência na sala de aula. Dentre dessa temática, pode-se questionar: a concepção de inclusão do professor do ensino regular muda no decorrer do ano ...
Ana Paula Húngaro Monteiro +1 more
doaj +1 more source
Towards Industrialized Conception and Production of Serious Games [PDF]
, 2009 Serious Games (SGs) have experienced a tremendous outburst these last years. Video game companies have been producing fun, user-friendly SGs, but their educational value has yet to be proven.
George, Sébastien +4 more
core +4 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source