Results 91 to 100 of about 851,834 (314)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

How to Identify Scientifc Revolutions? [PDF]

open access: yes, 2010
Conceptualizing scientific revolutions by means of explicating their causes, their underlying structure and implications has been an important part of Kuhn's philosophy of science and belongs to its legacy.
Seselja, Dunja, Weber, Erik
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Teacher-learners' conceptions of learning: evidence of a "communalist" conception amongst postgraduate learners [PDF]

open access: yes, 1998
The final publication is available at Springer via http://dx.doi.org/10.1023/A:1003021132510.Recently, research on mature students' approaches to learning, conducted within a students'-experiences-of-learning framework, has suggested that these students ...
Cliff, Alan F
core  

Medieval Christian Dualist Perceptions and Conceptions of Biblical Paradise [PDF]

open access: yes, 2013
The article intends to draw attention to some of the most significant and telling appropriations of traditional themes of Biblical paradise in medieval Christian dualism (namely, Paulicianism, Bogomilism and related groups in Eastern Christendom and ...
Stoyanov, Yuri
core   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

POSITIVE ATTITUDES AND NEGATIVE OF THE STUDENTS IN THE LEARNING OF MATHEMATICS, ITS IMPACT ON THE REPROACH AND TERMINAL EFFICIENCY

open access: yesRa Ximhai, 2014
The present investigation aimed to problematize "the positive and negative attitudes of students in learning mathematics, their impact on disapproval index and terminal efficiency." It was held in the Academic Unit "Rubén Jaramillo" of the Autonomous ...
Ladislao Romero–Bojórquez   +2 more
doaj  

Legal Conceptions of Parenthood: Adoptive Parents as Stewards [PDF]

open access: yes, 2019
In this paper, I outline common conceptions of parenthood and assess the strengths and weaknesses of these models, including the proprietarian, consent, causal, and stewardship models.
Edwards, Ashlyn
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Toleration in Conflict

open access: yesMeridiano 47, 2017
FORST, Rainer; “Toleration in Conflict: Past and Present”; Cambridge University Press, United States of America, New York, 2013; 662 pp.
Thiago Corrêa Malafaia
doaj  

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