Results 131 to 140 of about 405,071 (261)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Nutritional self-management in chronic diseases: a conceptual analysis. [PDF]

open access: yesFront Public Health
Zhang L   +5 more
europepmc   +1 more source

Musical experience prior to traumatic exposure as a resilience factor: a conceptual analysis. [PDF]

open access: yesFront Psychol, 2023
Fraile E   +4 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Loneliness in caregivers of people with chronic illnesses: conceptual analysis according to Walker and Avant. [PDF]

open access: yesRev Bras Enferm
Medina CPC   +5 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

The Conceptual Analysis of Collaboration in the Occupational Therapy by Combining the Scoping Review Methodology. [PDF]

open access: yesInt J Environ Res Public Health, 2023
Sawada T   +5 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Understanding Navon: A detailed structural and conceptual analysis of a basic local-global task. [PDF]

open access: yesPsychon Bull Rev
Schweigkofler F   +5 more
europepmc   +1 more source

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