Results 91 to 100 of about 8,154,104 (309)

Representing Earth Science Concepts through Slowmation: Influences on Conceptual Change

open access: yeseTropic: electronic journal of studies in the tropics, 2015
It is well known that students arrive in science classrooms with pre-instructional ideas about science phenomena, and that often students’ ideas are not scientifically accurate representations of these phenomena.
Reece Mills   +2 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Conceptual Change in Group Discussion: An Exploratory Study

open access: yes, 2014
In this contribution, we discuss conceptual change in mathematics, as it takes place during social interaction in group-work in the classroom. We rely on a socio-cultural perspective, according to which the learning of mathematics takes place in a ...
BRANCHETTI L, MORSELLI F
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Multiple Representations and Students’ Conceptual Change in Science

open access: yes, 2017
Conducting research from the vantage point of conceptual change and multiple representations can provide a powerful theoretical framework for better understanding of teaching and learning in science.
Won, Mihye   +4 more
core  

Conceptual Change in Science Teaching and Learning: Introducing the Dynamic Model of Conceptual Change

open access: yesInternational Journal of Educational Psychology, 2018
Conceptual change can be a challenging process, particularly in science education where many of the concepts are complex, controversial, or counter-intuitive.
Louis S. Nadelson   +4 more
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Reconsidering conceptual change. Issues in theory and practice

open access: yes, 2002
The bok is an important account of the state of the art of both theoretical and practical issues in the present-day research on conceptual ...
M., Limon, Mason, Lucia
core  

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