Results 151 to 160 of about 2,244,720 (326)

Performance Analysis and Conceptual Design of Lightweight UAV for Urban Air Mobility [PDF]

Francesco Mazzeo, Emanuele L. de Angelis, Fabrizio Giulietti, Alessandro Talamelli, Francesco Leali   +4 more
openalex   +1 more source

An advanced technology space station for the year 2025, study and concepts [PDF]

A survey was made of potential space station missions that might exist in the 2020 to 2030 time period. Also, a brief study of the current state-of-the-art of the major subsystems was undertaken, and trends in technologies that could impact the ...
Butterfield, A. J., Cuddihy, W. F., Garn, P. A., King, C. B., Queijo, M. J.   +4 more
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Design of the data-driven software application for identification, population monitoring, and risk assessment for lions in Serengeti Tanzania [PDF]

Computational Ecology and Software
This study presents a design of a Data-Driven software application for identification, population monitoring, and risk assessment for lions in Serengeti Tanzania.
Ambokile Okey, Devotha Nyambo, Shubi Kaijage, et al.   +2 more
doaj  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Evaluation of product conceptual design based on Pythagorean fuzzy set under big data environment. [PDF]

Sci Rep, 2022
Ma LD, Wang WX, Xie JW, Zhang N, Hu NF, Wang ZA.   +5 more
europepmc   +1 more source

A MHD channel study for the ETF conceptual design [PDF]

The procedures and computations used to identify an MHD channel for a 540 mW(I) EFT-scale plant are presented. Under the assumed constraints of maximum E(x), E(y), J(y) and Beta; results show the best plant performance is obtained for active length, L is
Smith, J. M., Staiger, P. J., Wang, S. Y.   +2 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Conceptual design of the Hybrid Ring with superconducting linac. [PDF]

J Synchrotron Radiat, 2022
Harada K, Funamori N, Yamamoto N, Shimosaki Y, Shimada M, Miyajima T, Umemori K, Sakai H, Nakamura N, Sakanaka S, Kobayashi Y, Honda T, Nozawa S, Nakao H, Niwa Y, Wakabayashi D, Amemiya K, Igarashi N.   +17 more
europepmc   +1 more source

The PIP-II Conceptual Design Report

, 2017
M.J. Ball, A. Burov, Brian Chase, Anindya Chakravarty, A. Chen, Stephen Dixon, Jonathan Edelen, Anna Grassellino, Dean Johnson, Stephen D. Holmes, S. Kazakov, Arkadiy Klebaner, I. Kourbanis, A. Leveling, Oleksandr Melnychuk, David Neuffer, T. Nicol, J.-F. Ostiguy, R. Pasquinelli, Donato Passarelli, L. Ristori, W. Pellico, J. Patrick, L. Prost, Igor Rakhno, A. Saini, W. Schappert, A. Shemyakin, J. Steimel, V. Scarpine, A. Vivoli, A. Warner, V. I. Yakovlev, P. N. Ostroumov, Zachary Conway   +34 more
openalex   +2 more sources