Results 71 to 80 of about 329,719 (257)
Building information modeling (BIM) is increasingly used during the conceptual design phase, which focuses on simulations such as energy usage analysis and comfort levels, like temperature and lighting conditions, to enhance user experience and well ...
Balamaheshwaran Renganathan +2 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Editorial: Transformable structures and envelopes in architecture and civil engineering
Marios C. Phocas, Maria Matheou
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Outcomes of the DeepWind Conceptual Design
AbstractDeepWind has been presented as a novel floating offshore wind turbine concept with cost reduction potentials. Twelve international partners developed a Darrieus type floating turbine with new materials and technologies for deep-sea offshore environment. This paper summarizes results of the 5 MW DeepWind conceptual design.
Paulsen, US (author) +9 more
openaire +6 more sources
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
The objective of this study is to design, develop, and analyze a tri-wheeled trolley integrated with a motor that incorporates adjustable and foldable features.
Howard Jun Hao Oh +5 more
doaj +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Conceptual Design for Sensemaking [PDF]
Blandford, A, Faisal, S, Attfield, S
openaire +2 more sources

