Results 81 to 90 of about 2,244,720 (326)
Initial weight estimation of twin-fuselage configuration in aircraft conceptual design
, 2022 Yiyuan Ma, Yan Jin, Ali Elham
openalex +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Novel Computer-Aided Design-Based Collaboration Framework for the Conceptual–Embodiment Design Phase
DesignsCollaborative production is growing in its importance to the global economy, and along with it, so are other collaborative activities along the production chain, such as collaborative design. Nowadays, collaborative detail design can be implemented using
Fariz Muharram Hasby +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Conceptual design of a process plant for the production of plantain flour
Cogent Engineering, 2016 Plantain has become an essential source of food in the Nigerian market today and to this effect, it is fast becoming a sought-after fruit, especially for persons diagnosed with diabetics. Being a perishable fruit, plantain is usually processed into flour
Sesan Peter Ayodeji
doaj +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Efficient Methodology for Power Management Optimization of Hybrid-Electric Aircraft
AerospaceThis paper presents an effective simplified model to optimize the mission power management supply for hybrid-electric aircraft in the conceptual design phase.
Giuseppe Palaia +2 more
doaj +1 more source
New conceptual model for design development of smart clothing [PDF]
, 2005 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Smart Clothing, the convergent future of the electronics and clothing industries, struggles to reach its true potential and enter the mass market because of
Ariyatum, Busayawan
core
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
TechnologiesBuilding information modeling (BIM) is increasingly used during the conceptual design phase, which focuses on simulations such as energy usage analysis and comfort levels, like temperature and lighting conditions, to enhance user experience and well ...
Balamaheshwaran Renganathan +2 more
doaj +1 more source