Results 91 to 100 of about 397,590 (315)

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Query-Based Multicontexts for Knowledge Base Browsing: an Evaluation

, 2006
Tane J, Cimiano P, Hitzler P. Query-Based Multicontexts for Knowledge Base Browsing: an Evaluation. In: Schärfe H, Hitzler P, Øhrstrøm P, eds. Conceptual Structures: Inspiration and Application: 14th International Conference on Conceptual Structures ...
Schärfe, Henrik, Øhrstrøm, Peter, Tane, Julien, Hitzler, Pascal, Cimiano, Philipp ; https://orcid.org/   +4 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Supporting ‘successful knowledge transfer’ for early childhood professionals – an emerging conceptual framework in an Australian context

, 2022
A wealth of literature exists that describes the process of knowledge transfer (KT) as activities, interactions and mechanisms that foster the dissemination, application, and contextualisation of acquired learning into practice.
Sharpe, Susan, Brown, Alice, Andrews, Dorothy   +2 more
core   +1 more source

An Analysis of Primary School Students’ Conceptual Knowledge of Geometric Solids

Kuramsal Eğitimbilim Dergisi, 2013
This study aims to analyze and interpret primary school students’ conceptual knowledge of geometric solids. For this reason, a diagnosis test consisting of three questions which measure primary school students’ conceptual knowledge of cube, square prism ...
Lütfi İNCİKABI, Çiğdem KILIÇ
doaj   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Special issue on conceptual modeling - 34th International Conference on Conceptual Modeling (ER 2015) [PDF]

, 2017
Paul Johannesson; Mong Li Lee; Liddle, S.; Opdahl, A.; Pastor López, O. (2017). Special issue on conceptual modeling - 34th International Conference on Conceptual Modeling (ER 2015). Data & Knowledge Engineering. 109:1-2.
Stephen Liddle, Oscar Pastor, Paul Johannesson, Li Lee, Mong, Opdahl, Andreas, Pastor, Oscar, Andreas L. Opdahl, Liddle, Steve, Pastor López, Oscar, Johannesson, Paul,, Liddle, Stephen, Opdahl, Andreas L., Mong Li Lee   +12 more
core   +1 more source

The impacts of using concept conceptual maps on mathematics students' understanding of trigonometric functions [PDF]

رویکردهای نوین آموزشی, 2012
The main purpose of this research was to study and recognize the effect of using concept maps as an assessment tool in students' learning of trigonometric functions.
E. Reyhani, Sh. Bakhshalizadeh, M. Ostadi   +2 more
doaj