Results 71 to 80 of about 397,590 (315)
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, EarlyView.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
Reason Maintenance - Conceptual Framework [PDF]
, 2009 This paper describes the conceptual framework for reason maintenance developed as part of ...
Bry, François, Kotowski, Jakub
core +1 more source
Frontiers in EducationIntroductionWhereas it is commonly assumed that in learning science, representational competence is a critical prerequisite for the acquisition of conceptual knowledge, comprehensive psychometric investigations of this assumption are rare. We undertake a
Peter Adriaan Edelsbrunner +2 more
doaj +1 more source
Journal of Research in Education Sciences, 2010 重複樣式的經驗對於掌握事物的規律性與發展代數思維甚為重要。本文以5 歲和6 歲各30 多名及8 歲兒童40 名進行找單位作業和下一色作業，指出偵測重複樣式的程序性知識包括：設定切割點、編碼、比對、複製或修正的迴路等四個步驟，也討論了限定原則與等長原則等概念性知識。5、6 歲兒童雖有近95%具備兩種概念性知識，卻有25%無法與程序性知識恰當地統整以找到單位。8 歲兒童在實驗所用的樣式結構下，幾乎可完全正確地找到單位，但在預測下一色的作業中卻有生產性的缺陷，會因未採用找單位的方式解題 ...
吳昭容 Chao-Jung Wu +1 more
doaj +1 more source
Conceptual Knowledge Markup Language: An introduction
Netnomics, 2000 26 pages, 8 tables, 4 ...
openaire +2 more sources
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Representing knowledge patterns in a conceptual database design aid : a dual-base knowledge model [PDF]
The current status of the Knowledge-Based Database Design Systems (KBDDSs) is reviewed. It is shown that they do not resolve the problems of the identification of the relevant objects (relations) and the interpretation of the identified objects from ...
Chang, Tsiar-Yuan
core
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
A perspective and framework for the conceptual modelling of knowledge
, 2012 Conceptual modelling of knowledge has remained an open research challenge. Existing frameworks do not cope with problems such as multiple user viewpoints, the plurality of epistemologies and representational forms, the mutability of knowledge, and the ...
Pigott, Diarmuid, Diarmuid J Pigott
core
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source