Results 51 to 60 of about 397,590 (315)

The relationship between grade 11 learners’ procedural and conceptual knowledge of algebra

Journal of Research and Advances in Mathematics Education, 2021
The acquisition of procedural and conceptual knowledge is imperative for the development of problem solving skills in mathematics. However, while there are mixed research findings on the relationship between the two domains of knowledge in some branches ...
Munyaradzi Chirove, Ugorji Iheanachor Ogbonnaya   +1 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

How and Why does the Multiplication Method Developed by the Russian Peasants Work?

Araştırma Temelli Etkinlik Dergisi, 2018
In this article, an activity designed and implemented to improve both procedural knowledge and conceptual knowledge of multiplication is introduced. The students were physically and mentally active while exploring a multiplication method developed by the
Bekir Cevizci
doaj   +2 more sources

Design as a learning opportunity in biology lessons—a cross-domain STEM approach and its impact on biological subject knowledge

Frontiers in Education
There is a broad consensus in politics, economy and science about the importance of promoting STEM competences. To promote STEM skills in the classroom, we propose a cross-domain approach combining the STEM sub-domains of Biology and Technology ...
Markus Reiser, Martin Binder, Holger Weitzel   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

The Model of Educational Reconstruction: Students’ Conceptual Knowledge on Solid State Chemistry Domain

Jurnal Pendidikan IPA Indonesia, 2018
Solid state chemistry (SSC) concept is abstract yet makes it difficult for students. Considering students’ and scientist conception in designing a learning sequence, it is important to make scientific knowledge to be comprehensible for students. Model of
E. Nursa'adah, L. Liliasari, A. Mudzakir, H. D. Barke   +3 more
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

The semantic content of concrete, abstract, specific, and generic concepts

Language and Cognition
ion processes involve two variables that are often confused with one another: concreteness (banana versus belief) and specificity (chair versus furniture or Buddhism versus religion).
Caterina Villani, Adele Loia, Marianna M. Bolognesi   +2 more
doaj   +1 more source

Propuesta de un test para determinar el conocimiento conceptual de estudiantes universitarios sobre la constante de equilibrio químico y su aplicación en estudiantes españoles

Química Nova, 2014
This article outlines a procedure that was used to develop a written test for evaluating the conceptual knowledge of chemical equilibrium constant among university students.
Manel Martínez-Grau, Joan Josep Solaz-Portolés, Vicent Sanjosé   +2 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source