Results 41 to 50 of about 397,590 (315)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Integrating multidisciplinary engineering knowledge
, 2012 This is an Accepted Manuscript of an article published by Taylor & Francis in Teaching in Higher Education on 13 June 2012, available online: http://dx.doi.org/10.1080/13562517.2012.694105.In order to design two distinct engineering qualification levels ...
Luckett, Kathy +3 more
core +1 more source
How we use what we learn in Math: An integrative account of the development of commutativity.
Frontline Learning Research, 2014 One of the crucial issues in mathematics development is how children acquire mathematical concepts and procedures. Most researchers now agree that this knowledge develops iteratively (e.g., Resnick, 1992).
Hilde Haider +5 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Knowledge evaluation in product lifecycle design and support [PDF]
, 2014 Enterprises are focusing more and more on knowledge issues for global product development. This paper describes knowledge evolution processes in product development activities and proposes a knowledge evaluation method in product lifecycle design.
SUGIMOTO, Shigeo +4 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Frontiers in Psychology, 2014 Traditionally neuropsychological observations have constrained the view that semantic knowledge is organized in categories: animals, plants or tools (Warrington & Shallice, 1984; Caramazza & Shelton, 1998; Tyler & Moss, 2001).
Luca Piretti +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Knowledge formalization in experience feedback processes : an ontology-based approach [PDF]
, 2008 Because of the current trend of integration and interoperability of industrial systems, their size and complexity continue to grow making it more difficult to analyze, to understand and to solve the problems that happen in their organizations. Continuous
Kamsu-Foguem, Bernard +3 more
core +1 more source
Effects of Emotional Experience in Lexical Decision
Frontiers in Psychology, 2016 Previous research has examined the effects of emotional experience (i.e., the ease with which words evoke emotion information) in semantic categorization, word naming, and Stroop tasks (Moffat, Siakaluk, Sidhu, & Pexman, 2015; Newcombe, Campbell ...
Paul D Siakaluk +6 more
doaj +1 more source