Results 111 to 120 of about 11,269 (252)
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
1769-1885 - Conceptual California Maps, David Hornbeck and David Fuller
, 2018 Conceptual maps from the 1983 publication, California Patterns: A Geographical and Historical Atlas by David Hornbeck in collaboration with cartographer, David Fuller, depicting California missions, presidios, pueblos, Spanish land concessions, Mexican ...
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European Journal of PhilosophyAbstractThe blossoming literature on genealogy in recent years has come as somewhat of a pleasant surprise to the historically inclined among us. It has not, however, come without its difficulties. As I see it, the literature on genealogy is guilty of two conflations, what I call the “debunking/problematizing conflation” and the “problematizing ...
openaire +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Conceptual maps, mental maps and timelines: learning objects in Ruralnet
, 2010 Uno de los indicadores de calidad en la formación virtual está íntimamente relacionado con el tipo de prácticas formativas que se proponen a los discentes para activar sus procesos cognitivos y favorecer la adquisición del conocimiento.
Villalustre Martínez, Lourdes +1 more
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Using concept maps to assess student's conceptual understanding [PDF]
, 2015 Konceptualne mape omogućuju učenicima jasan i transparentan prikaz razumijevanja te olakšavaju i omogućuju smisleno učenje, jer služe kao grafički predložak u strukturiranju znanja.
Gavrić, Branka
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Software bullet represented by conceptual maps
, 2018 This dissertation presents a proposal for a package insert for software, which allows to capture information related to the characteristics and functionalities of a certain software, following a predefined structure.
Martinez, Patrícia Valério
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