Results 191 to 200 of about 622,206 (305)

Application of a Conceptual Model for Translational Science Impact. [PDF]

J Clin Transl Sci
Presley JH, Worrell S, Jauregui-Dusseau A, Madden CA, James LP.   +4 more
europepmc   +1 more source

Conceptual change with refutational maps

, 2011
The purpose of this research was to explore the effect of studying refutational maps on conceptual change. Refutational maps are diagrams that explicitly present correct conceptions and commonly held misconceptions. A sample of 120 participants was randomly assigned into three groups: a refutational map group, a refutational text group and a non ...
openaire   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Unresolved questions on the GADD45GIP1-RPL35 axis in osteosarcoma: mechanistic links to ER stress and therapeutic targeting. [PDF]

Cancer Cell Int
Qi L, Gu Q, Yang D, Ye Z, Li D.
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Defining a public health approach to substance use: insights from a systematic scoping review and conceptual framework development approach. [PDF]

BMC Public Health
Mathias H, Gehring ND, Hammond RM, Navarrete J, Crépault JF, Emerson B, Markov A, Kosteniuk B, Speed K, Candler E, Dyck G, Galarneau LR, Issa T, Alvarado JCO, Campbell S, Hyshka E.   +15 more
europepmc   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Matters arising: a critique of "Nuancing the continuum from ideal to real-world implementation" by Eldh et al. 2025. [PDF]

Implement Sci Commun
Nilsen P, Kirk JW, Gunnarsson KU, Thomas K.   +3 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Editorial: Indigeneities

On_Culture, 2018
The Editorial Team
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