Results 41 to 50 of about 113,206 (264)

"Conceptual Space ": an Approach to the Development of Semantic Web [PDF]

open access: yesبازیابی دانش و نظام‌های معنایی, 2017
Semantic Web as the third generation of the Web is due to greater interaction between humans and computers and attempts to understand the processing of information for the machine in order to establish relationships between Web pages in such a way as to ...
Khadijeh Moradi
doaj   +1 more source

Metafora Konseptual Bertema Rihlah (Jalan-Jalan) pada Majalah Gontor: Analisis Semantik Kognitif

open access: yesDiglosia, 2021
This research is a cognitive semantic analysis and uses descriptive qualitative methods. The problems discussed in this study are the types of conceptual metaphors, namely (1) structural metaphors, (2) orientational metaphors, (3) metaphors.
Trian Ramadhan Nuryadin, Tajudin Nur
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Role of Conceptual Metonymy in Meaning Construction

open access: yes, 2004
In diesem Artikel argumentieren wir, dass abstrakte Schlussprinzipien, die auf Griceschen Maximen oder sogar nur auf einem einzigen Relevanzprinzip beruhen, nicht angemessen erklären können, wie Interaktanten Äußerungsbedeutungen tatsächlich erschließen.
Panther, Klaus-Uwe, Thornburg, Linda L.
openaire   +3 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

The means of expression of the conceptual-cognitive frame «Woman» [PDF]

open access: yesYazyk i kul'tura, 2015
This article presents a study of the means of expression of the conceptual-cognitive frame "Woman". It contains a logical-semantic classification of the attributive-nominative constructions with the nuclear lexeme "woman", as well as the analysis of the quantitative data.
openaire   +4 more sources

Meaning Extensions of Grasp: A Corpus-Based Study

open access: yesLexis: Journal in English Lexicology, 2010
By means of a lexico-semantic analysis, the aim of this paper is to provide a clearer picture of how the Eng­lish verb grasp is used in actual language production. The material for the analysis has been gathered from the 100 million word British National
Marie Nordlund
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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