Results 101 to 110 of about 1,908,176 (323)
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
COVID-19 and contact tracing apps: The importance of theory and conceptual models. [PDF]
Int J Med Inform, 2023 Jannati N.
europepmc +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Key characteristics of patient complexity and patient complexity conceptual models/measurement tools: a scoping review protocol. [PDF]
BMJ Open, 2023 Mutai R +3 more
europepmc +1 more source
Conceptual Model and System for Genre-Focused Interactive Storytelling [PDF]
, 2014 Börje F. Karlsson, Antônio L. Furtado
openalex +1 more source
Actors vs Shared Memory: two models at work on Big Data application frameworks [PDF]
, 2015 This work aims at analyzing how two different concurrency models, namely the shared memory model and the actor model, can influence the development of applications that manage huge masses of data, distinctive of Big Data applications.
Crafa, Silvia, Tronchin, Luca
core
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Applications of conceptual models from lifecourse epidemiology in ecology and evolutionary biology. [PDF]
Biol Lett, 2022 Laubach ZM +4 more
europepmc +1 more source