Results 81 to 90 of about 1,910,103 (290)

What is a Library Website, Anyway? Reconsidering Dominant Conceptual Models

Partnership: The Canadian Journal of Library and Information Practice and Research, 2021
In late 2019, Thompson Rivers University embarked on a multi-phase website usability project beginning with a website user survey, to be followed shortly afterward by usability testing and interviews.
Amy Paterson
doaj  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

VISUAL MODELS OF SYSTEMS ENGINEERING OF ADDITIVE MANUFACTURING PROCESSES

Надежность и качество сложных систем
Background. The paper discusses methods for using visual systems engineering tools using the example of additive manufacturing processes. Materials and methods.
A.I. Vlasov, G.A. Volkov, K.V. Selivanov
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Are we talking the Same Language? Challenging Complexity in Country Brand Models [PDF]

, 2014
The purpose of this paper is to review recent research into country brand models and identify the most common and shared dimensions. Based on the literature review, this study establishes a conceptual framework to consider the complex interaction between
Mariutti, F, Tench, R
core  

Supply chain integration-performance nexus in emerging & developing economies: a systematic review

Cogent Business & Management
The literature on SCI-performance nexus remains inconclusive and inconsistent. This study analyses the most recent literature aiming to clarify the most important conceptualisations of SCI, identify existing performance measures, and assess the evidence ...
Goitom Abera Baisa, Dante Benjamin Matellini, Ian D. Jenkinson, Chia-Hsun Chang   +3 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Climate and Human Behavior Studies for Our Warming World: An Introduction to the Models, Methods, and Data

Advances in Archaeological Practice
This article is an introduction and guide to investigating past relationships between climate and human behavior. Improving understanding of these relationships is essential as humanity confronts the challenges of our warming world.
Scott E. Ingram
doaj   +1 more source