Results 81 to 90 of about 366,121 (313)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Development and application of a rainfall-runoff model for semi-arid regions
RBRH, 2020 Despite the advances undertaken in recent years, modeling watershed’s hydrological responses remains a complex task, especially in data-scarce areas. In order to overcome this, new models with distinct representations of hydrological processes continue ...
José Almir Cirilo +5 more
doaj +1 more source
Complexity measures for object-oriented conceptual models of an application domain. [PDF]
According to Norman Fenton few work has been done on measuring the complexity of the problems underlying software development. Nonetheless, it is believed that this attribute has a significant impact on software quality and development effort.
Dedene, Guido, Poels, Geert
core
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
From conceptual models to constrained web forms
, 2002 Constraints expressed within document definitions, data models, ontologies, and domain models, are a key constituent of the Semantic Web. Indeed, Semantic Web applications will rely on these constraints when reasoning about Web contents. This paper deals
Dumas, M. Marlon +2 more
core
A cookbook for temporal conceptual data modelling with description logic
, 2014 We design temporal description logics suitable for reasoning about temporal conceptual data models and investigate their computational complexity. Our formalisms are based on DL-Lite logics with three types of concept inclusions (ranging from atomic ...
Ryzhikov, Vladislav +4 more
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
mSystems, 2019 Accurate predictions across multiple fields of microbiome research have far-reaching benefits to society, but there are few widely accepted quantitative tools to make accurate predictions about microbial communities and their functions.
Eric Sakowski +29 more
doaj +1 more source
Reason Maintenance - Conceptual Framework [PDF]
, 2009 This paper describes the conceptual framework for reason maintenance developed as part of ...
Bry, François, Kotowski, Jakub
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source