Results 61 to 70 of about 366,121 (313)

A Systems Thinking Approach to Integrated STEM in School-Based Agricultural Education

open access: yesEducation Sciences
The content and career cluster of agriculture, food, and natural resources (AFNR) provides opportunities for K-12 teachers to engage students to solve complex authentic problems that blend science, technology, engineering, and mathematics (STEM), yet ...
Neil A. Knobloch   +3 more
doaj   +1 more source

Identifiers within conceptual models and standards

open access: yesJLIS.it, 2022
Identifiers are numeric or alphanumeric strings of characters permanently and uniquely associated with a resource to ensure stable access to it and its metadata. They play a fundamental role in the semantic web as they guarantee interoperability between
Laura Manzoni
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Conceptual framework (Hypothesized models).

open access: yes, 2022
Conceptual framework (Hypothesized models).
Bishnu Khanal (14160413)   +4 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

New Conceptual Model for the Magma-Hydrothermal-Tectonic System of Krafla, NE Iceland

open access: yesGeosciences, 2020
The complexity of the Krafla volcano and its geothermal system(s) has puzzled geoscientists for decades. New and old geoscientific studies are reviewed in order to shed some light on this complexity. The geological structure and history of the volcano is
Knútur Árnason
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Interconnected pathways: Social determinants of health, infections, and Alzheimer's disease and related dementias

open access: yesAlzheimer’s & Dementia: Translational Research & Clinical Interventions
Social determinants of health (SDOH), infections, and Alzheimer's disease and related dementias (ADRD) are interconnected through complex pathways. Existing research establishes associations between SDOH and infections, between SDOH and ADRD, and between
Juehyun Shin   +2 more
doaj   +1 more source

Biogeochemical Interactions In The Application Of Biotechnological Strategies To Marine Sediments Contaminated With Metals

open access: yesNova Biotechnologica et Chimica, 2015
Sediment contamination in coastal areas with high anthropogenic pressure is a widespread environmental problem. Metal contaminants are of particular concern, since they are persistent and cannot be degraded. Microorganisms can influence metal mobility in
Fonti Viviana   +2 more
doaj   +1 more source

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