Results 51 to 60 of about 366,121 (313)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Knjižnica, 2009 Two studies in connection with the Functional Requirements for Bibliographic Records (FRBR) conceptual model are presented. While the model is based on experiences of experts, it is yet to have been tested in practice.
Jan Pisanski, Maja Žumer
doaj +1 more source
Simulating interactions between saturated and unsaturated storage in a conceptual runoff model [PDF]
, 2003 There is an increasing demand for modelling the fluxes of chemical constituents at the catchment scale. Conceptual runoff models provide a basis for such modelling tasks provided that they capture the essential hydrological processes.
Jan Seibert +7 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Il nuovo modello concettuale dell’universo bibliografico: FRBR Library Reference Model
AIB Studi, 2016 Il dibattito su FRBR library reference model qui esposto è basato sul testo 2016 destinato alla worldwide review. Si mettono in evidenza alcuni aspetti innovativi di FRBR-LRM rispetto ai precedenti modelli della famiglia FRBR e si espongono alcune ...
Pat Riva
doaj +1 more source
Conceptual modelling: framework, principles, and future research [PDF]
, 2007 The conceptual modelling task in a simulation project is very important and yet is still generally regarded as more of an art than a science. The meaning and nature of conceptual modelling are discussed and a framework set out.
Brooks, R J
core
Near real-time collaborative conceptual modeling on the web
, 2022 S.344-357Collaboration during the creation of conceptual models is an integral pillar of design processes in many disciplines. Synchronous collaboration, in particular, has received little attention in the conceptual modeling literature so far. There are
Derntl, Michael +4 more
core +1 more source
International Journal of Computing, 2014 Decision making is mostly based on decision concepts and decision models built in decision support systems. Type of decision problem determines application. This paper presents a conceptual decision model that utilises rule- based methodologies, numerical algorithms and procedures, statistical methodologies including distributions, and visual support ...
openaire +2 more sources
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source