Results 71 to 80 of about 366,121 (313)

TECHNOLOGY MODERNIZATION IN THE MINING SECTOR: MODELS AND EFFECTS

open access: yesСевер и рынок: формирование экономического порядка, 2023
Amidst the current shift towards sustainable development and a low-carbon economy, it is important to assess the preparedness of mining companies for implementing large-scale technology modernization programs.
Andrey Yu. Abrashitov   +1 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

On the evolution of conceptual modeling

open access: yes, 2008
Since the 1980s the need increased for overcoming idiosyncrasies of approaches to modeling in the various sub-disciplines of computing. The theoretical model of evolution is used in this paper for analyzing how computing and conceptual modeling have changed.
openaire   +4 more sources

The Conceptual LeanPPD Model [PDF]

open access: yes, 2010
This paper is presenting the conceptual Lean Product and Process Development (LeanPPD) model which is a project funded by the EU-PF7. The project is addressing the needs of European manufacturing companies of a new model that goes beyond lean manufacturing, to ensure the transformation of the enterprise into lean environment.
Ahmed Al-Ashaab   +8 more
openaire   +2 more sources

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Catalogues, conceptual models, data model: the orientations of research and the thematic guidelines in Library and information science

open access: yesBibliothecae.it, 2016
The adoption of new conceptual models for bibliographic and authority data, the latest normative structures of the catalogue, the language of data encoding and their communication in semantic Web, are some of the factors that are transforming library ...
Antonella Trombone
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

The Comparison of the Efficieny of MCDM Models in site Selection of Flood Spread in GIS Environment (Case Studey: Garabaygan Catchment) [PDF]

open access: yesنشریه جغرافیا و برنامه‌ریزی, 2014
The selection of suitable location for implementing of flood spreading project and artificial recharge of aquifers is an important step. To assess this purpose, the Geographic Information System (GIS) conceptual models and decision making systems were ...
Hasan ali Faraji Sabokbar   +3 more
doaj  

Incorporating business requirements and constraints in database conceptual models

open access: yes, 2004
Entity relationship (ER) approach is predominantly used for conceptual modelling of database systems in terms of entities and their relationships. The approach does not provide sufficient support for incorporating business constraints and their impact on
Khan, Khaled M.   +2 more
core  

A new conceptual design method to support rapid and effective mapping from product design specification to concept design

open access: yes, 2016
Conceptual design has a decisive impact on the product development time, cost and success. This paper presents a new conceptual design method for achieving rapid and effective mapping from product design specification (PDS) to concept design. This method
Li, Rong   +5 more
core   +1 more source

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