Results 101 to 110 of about 1,910,103 (290)

Conceptual Microarchitectures for Hydrologic Simulation Models

CLEI Electronic Journal, 2018
Mathmatical Hydrologic models simulate real world environmental processes through different strategies. Each process is calculated by means of methods that utilize physical parameters for representing the real world system.
Adriana Urciuolo, Iturraspe Rodolfo, Ariel Parson   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Formal software measurements for object-oriented business models. [PDF]

This paper presents a set of metrics and pseudo-metrics for the measurement of conceptual distances in M.E.R.O.D.E. business models. The measures are developed and validated using measure and measurement theory.
Dedene, Guido, Poels, Geert
core  

COVID-19 and contact tracing apps: The importance of theory and conceptual models. [PDF]

Int J Med Inform, 2023
Jannati N.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Actors vs Shared Memory: two models at work on Big Data application frameworks [PDF]

, 2015
This work aims at analyzing how two different concurrency models, namely the shared memory model and the actor model, can influence the development of applications that manage huge masses of data, distinctive of Big Data applications.
Crafa, Silvia, Tronchin, Luca
core  

Individual variation in undergraduate student metacognitive monitoring and error detection during biology model evaluation

Frontiers in Education
IntroductionModels are a primary mode of science communication and preparing university students to evaluate models will allow students to better construct models and predict phenomena.
Joseph Dauer, Mei Grace Behrendt, McKenna Elliott, Bethany Gettings, Tammy Long, Caron Clark   +5 more
doaj   +1 more source

Key characteristics of patient complexity and patient complexity conceptual models/measurement tools: a scoping review protocol. [PDF]

BMJ Open, 2023
Mutai R, Sugiyama Y, Aoki T, Matsushima M.   +3 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Applications of conceptual models from lifecourse epidemiology in ecology and evolutionary biology. [PDF]

Biol Lett, 2022
Laubach ZM, Holekamp KE, Aris IM, Slopen N, Perng W.   +4 more
europepmc   +1 more source