Seeking Causality in the Links between Time Perspectives and Gratitude, Savoring the Moment and Prioritizing Positivity: Initial Empirical Test of Three Conceptual Models. [PDF]
Burzynska-Tatjewska B +2 more
europepmc +1 more source
Complexity measures for object-oriented conceptual models of an application domain. [PDF]
According to Norman Fenton few work has been done on measuring the complexity of the problems underlying software development. Nonetheless, it is believed that this attribute has a significant impact on software quality and development effort.
Dedene, Guido, Poels, Geert
core
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Leadership and Environmental Sustainability: An Integrative Conceptual Model of Multilevel Antecedents and Consequences of Leader Green Behavior [PDF]
Hannes Zacher +3 more
openalex +1 more source
Perceived Value and Customers Satisfaction in Hotel Industry: A Systematic Conceptual Model [PDF]
Bachrudin Saleh Luturlaen
openalex +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
A conceptual model of online hotel booking: the role of online review and online trust towards online booking intention / Fadhlina Mahat... [ et al.] [PDF]
Fadhlina Mahat +5 more
openalex
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Reconciling land sharing and sparing: a conceptual model for land use [PDF]
Marco Fioratti Junod +4 more
openalex +1 more source

