Results 161 to 170 of about 23,828,011 (387)
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
Beyond the detection of students´ mental models. An integrative representational approach [PDF]
Investigações em Ensino de Ciências, 2002 In this paper we initially discuss some limitations of the mental model theoretical framework for research in science education. Then, after an analysis of Vergnaud´s conceptual fields theory we propose an approach that integrating elements of both ...
Ileana Maria Greca +1 more
doaj
Family as a health promotion setting: A scoping review of conceptual models of the health-promoting family. [PDF]
PLoS One, 2021 Michaelson V, Pilato KA, Davison CM.
europepmc +1 more source
Conceptual Modeling: Topics, Themes, and Technology Trends [PDF]
ACM Computing Surveys. 55 (14), pp. 1-38 (2023)Conceptual modeling is an important part of information systems development and use that involves identifying and representing relevant aspects of reality. Although the past decades have experienced continuous digitalization of services and products that impact business and society, conceptual modeling efforts are still required to support new ...
arxiv
Molecular Oncology, EarlyView.Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane +16 more
wiley +1 more source
Students’ Concepts of the Trapezoid at the End of Lower Secondary Level Education
Open Education Studies, 2019 Understanding basic geometric concepts is important for the development of students’ thinking and geometric imagination, both of which facilitate their progress in mathematics.
Halas Zdeněk +3 more
doaj +1 more source
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
Molecular Oncology, EarlyView.We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas +15 more
wiley +1 more source
Seeking Causality in the Links between Time Perspectives and Gratitude, Savoring the Moment and Prioritizing Positivity: Initial Empirical Test of Three Conceptual Models. [PDF]
Int J Environ Res Public Health, 2022 Burzynska-Tatjewska B +2 more
europepmc +1 more source
Conceptual Modelling of Interaction
, 2011 The conceptual model of an information system cannot be considered to be complete after just specifying the structure and behaviour of the system. It is also necessary to specify how end users will interact with the system. Even though there are several proposals for modelling interaction, none of them have become widely known or widely used in ...
Aquino Salvioni, Nathalie Marylin +3 more
openaire +3 more sources