Results 121 to 130 of about 5,453,078 (289)
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Die konzeptuelle Metapher ZEIT ALS RAUM im FrameNet-Konstruktikon des Deutschen
Linguistik OnlineBased on the epistemological tenet that time and space are the two fundamental concepts of our thinking, this article presents a frame-semantic approach to the conceptualisation of time as space. It shows that the chosen cognitive linguistic approach is
Phillip Alexander Neumair
doaj +1 more source
Minus Space: survey exhibition
, 2008 This was a survey exhibition of MINUS SPACE at PS1 Contemporary Art Center (NYC). PS1 is affiliated with the Museum of Modern Art in New York, USA and is regarded as an important international institution for the exhibition of contemporary art.
Jenkins, Kyle
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A Conceptual and Analytical Framework for Interpreting the Spatiality of Social Life [PDF]
, 2009 This paper provides a framework for understanding the phenomenon of the discursive-material production of space, and also, for considering how unknowns may be organised.
Pugalis, Lee
core
The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Molecular Oncology, EarlyView.Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
Orbiting deep space relay station study. Volume 2: Conceptual design [PDF]
, 1979 The Orbiting Deep Space Relay Station conceptual design is described.
Hunter, J. A.
core
Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source
Solution Space Analysis for Robust Conceptual Design Solutions in Aeronautics
Engineering ProceedingsThe use of novel technologies for low-emission and more efficient aviation requires not only the achievement of a given technology readiness level, but also their integration into aircraft concepts.
Vladislav T. Todorov +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source