Results 101 to 110 of about 5,453,078 (289)

A Comprehensive Implementation of Conceptual Spaces

open access: yes, 2017
The highly influential framework of conceptual spaces provides a geometric way of representing knowledge. Instances are represented by points and concepts are represented by regions in a (potentially) high-dimensional space. Based on our recent formalization, we present a comprehensive implementation of the conceptual spaces framework that is not only ...
Lucas Bechberger, Kai-Uwe Kühnberger
openaire   +3 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

A connectionist approach to embodied conceptual metaphor

open access: yesFrontiers in Psychology, 2010
A growing body of data has been gathered in support of the view that the mind is embodied and that cognition is grounded in sensory-motor processes. Some researchers have gone so far as to claim that this paradigm poses a serious challenge to central ...
Stephen J Flusberg   +3 more
doaj   +1 more source

Lost in Conceptual Space : Metaphors of Conceptual Integration [PDF]

open access: yes, 2004
Conceptual integration theory (Fauconnier & Turner, 1998, 2002) is re-examined in the light of recent criticisms (e.g., Gibbs, 2000, 2001). It is argued that the assumption of four independent cognitive spaces enters the model primarily as an ...
Ritchie, L. David, L. David Ritchie
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Conceptual design for a 5 kWe space nuclear reactor power system

open access: yesNuclear Engineering and Technology
Enhancing the capabilities of unmanned space exploration, such as satellite monitoring and space science missions, requires efficient and reliable nuclear power systems.
Huaping Mei   +11 more
doaj   +1 more source

The Analysis of Conceptual Blends in Forough Farrokhzad's Collection of Poems "Believe in the Beginning of the Cold Season [PDF]

open access: yesپژوهشنامه ادب غنایی
Human life is entwined with metaphors, and language reflects how we understand the world through metaphors. One of the most important and recent theories in the field of metaphor constructing is the theory of conceptual blending, presented by Fauconnier ...
Sara Hosseini, Abbas ali Ahangar
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Exploring German High School Students’ Conceptual Learning Pathways of Space and Place

open access: yesEducation Sciences
Space and place, fundamental concepts in geography, uniquely contribute to the development of students’ geographical thinking. Despite this, these concepts are underrepresented in German geography classrooms, partly due to a distinct lack of empirical ...
Natalie Bienert
doaj   +1 more source

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