Results 111 to 120 of about 5,453,078 (289)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Conceptual approaches of the rural space [PDF]

open access: yes, 2014
This paper is a bibliographic study of the rural space concept, from its establishment and until now. In this respect, the following works from the dedicated literature have been studied: scientific works, doctoral dissertations, case studies, books and ...
Alecu, Ioan Nicolae   +3 more
core   +2 more sources

Understanding the CO2 Scrubber Used at the Space Analog for the Moon and Mars

open access: yes, 2023
Immediate accessThis item is made available by the University of Arizona Center for Human Space Exploration (CHaSE) with support from the University of Arizona Libraries.
Tresch, Trent
core   +1 more source

Semantic Representations in 3D Perceptual Space

open access: yesi-Perception, 2011
Barsalou's (1999) perceptual theory of knowledge echoes the pre-20th century tradition of conceptualizing all knowledge as inherently perceptual. Hence conceptual space has an infinite number of dimensions and heavily relies on perceptual experience ...
Suncica Zdravkovic, Petar Milin
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Piantanida Near Space Balloon Gondola Engineered Drawing and Details

open access: yes
Immediate accessThis item is made available by the University of Arizona Center for Human Space Exploration (CHaSE) with support from the University of Arizona Libraries.
Tresch, Trent
core   +2 more sources

The role of conceptual blending in the meaning construction of the Portuguese hedge “um tipo de”

open access: yesGragoatá, 2006
Based on Mental Space Theory, the main purpose of this article is to verify the role that conceptual blending plays in meaning construction of Portuguese hedge um tipo de. Analysing sentences containing that hedge, we conclude that the meaning of um tipo
Angelina Aparecida de Pina
doaj  

Conceptual problems in the body-space conceptualizations in A Cyborg Manifesto in the context of Sartori’s conceptual analysis

open access: yesCogent Arts & Humanities
A Cyborg Manifesto, one of the key texts of posthumanist theory, is frequently referenced in research across various fields such as science, philosophy, art, and design.
Oğuzhan Tüfenkci   +1 more
doaj   +1 more source

Computing Contrast on Conceptual Spaces.

open access: yes, 2019
This paper provides an updated formalization of the operation of contrast, and shows that, by applying it on conceptual spaces, membership functions to categories as e.g. those captured by adjectives or directional relationships emerge as a natural by-product.
Sileno, G.   +3 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy