Results 131 to 140 of about 1,966,627 (313)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Case conceptualization in clinical practice and training
Case conceptualization is central to the success of the therapeutic process. However, integrative case conceptualization research has lagged behind research on integrating therapeutic intervention techniques. A successful case conceptualization provides (
Gilboa-Schechtman, Eva
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Trauma-Informed Case Conceptualization
, 2020 Dr. Jon Sperry presented on, Trauma-Informed Case Conceptualization at the Universite Internationale de Casablanca in Casablanca, Morocco on Jan.
Sperry, Jon
core
Career Counseling-Focused Case Conceptualization
, 2021 Dr. Jon Sperry gives a two-day webinar, Career Counseling-Focused Case Conceptualization for the Career Development Association of ...
Sperry, Jon
core
Hierarchical Conceptualization in Polish and Slovene Word Formation Discourses
Slavia MeridionalisHierarchical Conceptualization in Polish and Slovene Word Formation Discourses The aim of the paper is to present the hierarchy as a multi-faceted conceptual category. The topic sets out at least two major research areas.
Paweł Kowalski
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Conceptualization Theory of Successful Breastfeeding
, 2019 Theory means a system of ideas intended to explain something. Explaining the facts which are absolutely right. This theory intends to explain regarding different concepts lies behind successful breastfeeding.
Manjubala Dash
core +1 more source
Conceptual HyperGraph and Conceptual SuperHyperGraph
Abstract. A finite hypergraph generalizes an ordinary graph by permitting a hyperedge to connect anynonempty subset of vertices, thereby capturing multiway interactions. Extending this idea, a finite SuperHyperGraph is obtained by iterating the powerset operation, producing nested families of vertex and edgesets that model multi-layer relational ...
openaire +3 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source