Results 141 to 150 of about 1,966,627 (313)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Cyber Dating Abuse: Conceptualization and Meta-analysis of Prevalence Rates
Anuario de Psicología JurídicaIn this study, a systematic review was carried out with the aim of analyzing the terms, definitions, dimensions, and prevalence rates of cyber dating abuse (CDA). After the analysis, the term cyber dating abuse is considered as the most appropriate and a
Ainize Martínez-Soto, Izaskun Ibabe
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Product Intelligence: Its Conceptualization, Measurement and Impact on Consumer Satisfaction
In the last decade, companies have developed a large number of intelligent products. Due to the use of information technology, these products, for example, are able to work autonomously, cooperate with other products, or adapt to changing circumstances ...
Hultink, E.J. +2 more
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Chwila i wieczność w poezji Jana Twardowskiego
Stylistyka, 2019 The aim of this paper is to present interpretations of two poems by Jan Twardowski, entitled przepiórka [a quail] and wieczność [eternity]. The interpretations focus on the conceptualization of two opposite TIME categories, MOMENT and ETERNITY.
JOLANTA KOWALEWSKA-DĄBROWSKA
doaj
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Inference, Language, and Situated Conceptualization [PDF]
The purpose of this writing is to exercise a philosophical lesson about the role of linguistic inference in cognitive science accounts of conceptualization. I argue that while it makes good sense to endorse the idea that our conceptual scheme comes about
Porto, Alexander
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