Results 61 to 70 of about 190,212 (326)
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Petri Nets and Other Models of Concurrency [PDF]
, 1998 This paper retraces, collects, and summarises contributions of the authors --- in collaboration with others --- on the theme of Petri nets and their categorical relationships to other models of ...
Nielsen, M., Sassone, V.
core +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Journal of the International AIDS Society, 2010 The notion that concurrent sexual partnerships are especially common in sub‐Saharan Africa and explain the region's high HIV prevalence is accepted by many as conventional wisdom.
Larry Sawers, Eileen Stillwaggon
doaj +1 more source
Modular Composition of Language Features through Extensions of Semantic Language Models [PDF]
, 1999 Today, programming or specification languages are often extended in order to customize them for a particular application domain or to refine the language definition. The extension of a semantic model is often at the centre of such an extension.
Pahl, Claus
core +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Frontiers in Public Health, 2021 Background: Alcohol consumption and distress have increased among Canadians since the start of the COVID-19 pandemic.Methods: We examined whether sociodemographic and COVID-19-related worries are associated with various combinations of alcohol ...
Fatima Mougharbel +12 more
doaj +1 more source
Convolution, Separation and Concurrency [PDF]
, 2014 A notion of convolution is presented in the context of formal power series together with lifting constructions characterising algebras of such series, which usually are quantales. A number of examples underpin the universality of these constructions, the
Dongol, Brijesh +2 more
core
Enhanced Operational Semantics in Systems Biology [PDF]
, 2003 We are faced with a great challenge: the cross-fertilization between the fields of formal methods for concurrency, in the computer science domain, and systems biology in the biological ...
A. Dovier +11 more
core +1 more source
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source