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Nonessential kinetochore proteins contribute to meiotic chromosome condensation through polo-like kinase. [PDF]
Trakroo D +3 more
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Condensin I confers Stiffness and Centromeric Cohesion to Mitotic Chromosomes
Nielsen CF +9 more
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Progressive chromosome shape changes quantified during cell divisions
Kakui Y +6 more
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Condensin: crafting the chromosome landscape
Chromosoma, 2013The successful transmission of complete genomes from mother to daughter cells during cell divisions requires the structural re-organization of chromosomes into individualized and compact structures that can be segregated by mitotic spindle microtubules. Multi-subunit protein complexes named condensins play a central part in this chromosome condensation
Ilaria, Piazza +2 more
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Condensin Regulation of Genome Architecture
Journal of Cellular Physiology, 2017Condensin complexes exist across all domains of life and are central to the structure and organization of chromatin. As architectural proteins, condensins control chromatin compaction during interphase and mitosis. Condensin activity has been well studied in mitosis but have recently emerged as important regulators of genome organization and gene ...
Vibhuti, Rana, Giovanni, Bosco
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Condensin: Architect of mitotic chromosomes
Chromosome Research, 2009Condensin is a highly conserved pentameric complex consisting of two structural maintenance of chromosome (SMC) ATPase subunits and three auxiliary components. While initially regarded as a key driver of mitotic chromosome condensation, condensin is increasingly viewed as having a more subtle influence on chromosome architecture.
Damien F, Hudson +2 more
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Exploring Condensins with Magnetic Tweezers
2017The signature activity of condensins as DNA reshaping machines is their ability to impose the giant loop architecture onto the chromosome. At the heart of this activity lies the propensity of the proteins to assemble into macromolecular clusters that bring distant DNA segments together.
Rupa, Sarkar, Valentin V, Rybenkov
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