Results 161 to 170 of about 6,249 (200)

Mitotic chromosomes harbor cell type- and species-specific structural features within a universal loop array conformation. [PDF]

Genome Res
Oomen ME, Fox AN, Gonzalez I, Molliex A, Papadopoulou T, Navarro P, Dekker J.   +6 more
europepmc   +1 more source

The Condensin II complex regulates essential gene expression programs during erythropoiesis.

Development
Abid D, Murphy K, Murphy Z, Rahman N, Getman M, Steiner L.   +5 more
europepmc   +1 more source

Complex rheology of condensin in entangled DNA

Conforto F, Valdes A, Vanderlinden W, Michieletto D.   +3 more
europepmc   +1 more source

Condensin I confers Stiffness and Centromeric Cohesion to Mitotic Chromosomes

Nielsen CF, Witt H, Ridolfi A, Kempers B, Chameau EM, van der Smagt S, Barisic M, Peterman EJ, Wuite GJ, Hickson ID.   +9 more
europepmc   +1 more source

Condensin II activation by M18BP1 [PDF]

Molecular Cell
ABSTRACT Condensin complexes promote the drastic spatial rearrangement of the genome upon mitotic entry. Condensin II initiates chromosome condensation in early mitosis. To prevent chromosome condensation during interphase, condensin II is inhibited by MCPH1, but the mechanism is unknown.
Erin E Cutts
exaly   +6 more sources

Differential Contributions of Condensin I and Condensin II to Mitotic Chromosome Architecture in Vertebrate Cells [PDF]

Cell, 2003
The canonical condensin complex (henceforth condensin I) plays an essential role in mitotic chromosome assembly and segregation from yeast to humans. We report here the identification of a second condensin complex (condensin II) from vertebrate cells.
Takao Ono, Ana Losada, Michiko Hirano
exaly   +5 more sources

Establishment of dsDNA-dsDNA interactions by the condensin complex [PDF]

Molecular Cell, 2023
Condensin is a structural maintenance of chromosomes (SMC) complex family member thought to build mitotic chromosomes by DNA loop extrusion. However, condensin variants unable to extrude loops, yet proficient in chromosome formation, were recently ...
Minzhe Tang, Georgiĭ Pobegalov, Hideki Tanizawa   +2 more
exaly   +3 more sources

Condensin I is required for faithful meiosis in Drosophila males [PDF]

Chromosoma, 2020
The heteropentameric condensin complexes play vital roles in the formation and faithful segregation of mitotic chromosomes in eukaryotes. While the different contributions of the two common condensin complexes, condensin I and condensin II, to chromosome
Stefan Heidmann
exaly   +2 more sources

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Condensin, master organizer of the genome

Chromosome Research, 2017
A fundamental requirement in nature is for a cell to correctly package and divide its replicated genome. Condensin is a mechanical multisubunit complex critical to this process. Condensin uses ATP to power conformational changes in DNA to enable to correct DNA compaction, organization, and segregation of DNA from the simplest bacteria to humans.
Paul Kalitsis, Kathryn M Marshall, Kalitsis Paul   +2 more
exaly   +3 more sources