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Contrasting roles of condensin I and condensin II in mitotic chromosome formation
2013In vertebrates, two condensin complexes exist, condensin I and condensin II, which have differing but unresolved roles in organizing mitotic chromosomes. To dissect accurately the role of each complex in mitosis, we have made and studied the first vertebrate conditional knockouts of the genes encoding condensin I subunit CAP-H and condensin II subunit ...
Green, LC +12 more
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Condensin, cohesin and the control of chromatin states
Current Opinion in Genetics & Development, 2013Cohesin and condensin complexes are essential for defining the topology of chromosomes through the cell cycle. Here we look at the emerging role of these complexes in regulating chromatin structure and gene expression and reflect on how these activities could be linked with chromosome topology.
Aragon, L +2 more
openaire +3 more sources
Common Fragile Sites Are Characterized by Faulty Condensin Loading after Replication Stress
Cell Reports, 2020Kumiko Samejima +2 more
exaly
Structural Basis for a Safety-Belt Mechanism That Anchors Condensin to Chromosomes
Cell, 2017Christian Haering +2 more
exaly