Results 61 to 70 of about 18,931,441 (264)

Labor Supply and Conditional Cash Transfer: Evidences from Tekoporã Program

Población y Desarrollo, 2019
This article searches understand the effects caused by the Conditional Cash Transfer Program Tekoporã of Paraguay in labor supply of participants. To achieve this purpose, a group of program participants was identified and, using the Propensity Score ...
Juan Carlos Núñez Guerrero
doaj   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Nonparametric Tests of Conditional Treatment Effects [PDF]

We develop a general class of nonparametric tests for treatment effects conditional on covariates. We consider a wide spectrum of null and alternative hypotheses regarding conditional treatment effects, including (i) the null hypothesis of the ...
Sokbae Lee, Yoon-Jae Whang
core   +2 more sources

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Asymmetry-Aware Local Structure Alignment for Conditional Average Treatment Effect Estimation

Proceedings of the 35th ACM International Conference on Information and Knowledge Management
Estimating conditional average treatment effect (CATE) is crucial for characterizing treatment effect heterogeneity at the individual or subgroup level. Existing methods mitigate confounding bias by capturing local structures within treatment and control
Ming-Shu Cao, Fu-Yuan Cao, Shi-Chang Qiao, Zhuo-Hong Tan   +3 more
semanticscholar   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif, Diane Demailly, Gabriella A. Horvàth, Juan Dario Ortigoza Escobar, Nathalie Dorison, Mayté Castro Jiménez, Cécile A. Hubsch, Thomas Wirth, Gun‐Marie Hariz, Sophie Huby, Morgan Dornadic, Zohra Souei, Muhammad Mushhood Ur Rehman, Simone Hemm, Mehdi Boulaymen, Eduardo M. Moraud, Jocelyne Bloch, Xavier Vasques   +17 more
wiley   +1 more source

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang, Jialin Du, Jinghui Liu, Dongmei Hu, Hongxin Wang, Xiaoxiao Man, Lehong Gao, Shimin Hu, Xianghong Meng, Hongyang Zhao, Minjing Hu, Yingxue Yang, Zhiqi Xiong, Liankun Ren   +13 more
wiley   +1 more source

Nonparametric Tests for Treatment Effect Heterogeneity [PDF]

A large part of the recent literature on program evaluation has focused on estimation of the average effect of the treatment under assumptions of unconfoundedness or ignorability following the seminal work by Rubin (1974) and Rosenbaum and Rubin (1983 ...
Richard K. Crump, Oscar A. Mitnik, V. Joseph Hotz, Guido W. Imbens   +3 more
core   +2 more sources

Heterogeneity in the treatment effect of sodium-glucose cotransporter-2 inhibitor on chronic kidney disease risk reduction: a prevalent new user cohort study applying double/debiased machine learning

Diabetology & Metabolic Syndrome
Background Despite strong evidence supporting the benefits of sodium-glucose cotransporter-2 inhibitor (SGLT2i) for managing type 2 diabetes, heterogeneity of treatment response is rarely assessed. This study aims to demonstrate the heterogeneity effects
Tanawan Kongmalai, Panu Looareesuwan, Amarit Tansawet, Sukanya Siriyotha, Patratorn Kunakorntham, Burin Boonwatcharapai, John Attia, Gareth J. McKay, Ammarin Thakkinstian   +8 more
doaj   +1 more source

Using the Bayesian credible subgroups method to identify populations benefiting from treatment: An application to the Look AHEAD trial.

PLoS ONE, 2020
Traditionally, subgroup analyses are used to assess whether patient characteristics moderate treatment effectiveness with general disregard for issues of multiplicity.
Anna Coonan, Patrick Schnell, Joel Smith, John Forbes   +3 more
doaj   +1 more source