Results 111 to 120 of about 142,210 (310)
Nonparametric tests of conditional treatment effects [PDF]
, 2009 We develop a general class of nonparametric tests for treatment effects conditional on covariates. We consider a wide spectrum of null and alternative hypotheses regarding conditional treatment effects, including (i) the null hypothesis of the ...
Whang, Yoon-Jae +5 more
core +1 more source
Advanced Science, EarlyView.Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng +8 more
wiley +1 more source
Noise Regularization for Conditional Density Estimation
CoRR, 2019 Modelling statistical relationships beyond the conditional mean is crucial in many settings. Conditional density estimation (CDE) aims to learn the full conditional probability density from data. Though highly expressive, neural network based CDE models can suffer from severe over-fitting when trained with the maximum likelihood objective.
Rothfuss, Jonas +6 more
openaire +3 more sources
Nonparametric Kernel Testing in Semiparametric Autoregressive Conditional Duration Model [PDF]
A crucially important advantage of the semiparametric regression approach to the nonlinear autoregressive conditional duration (ACD) model developed in Wongsaart et al. (2011), i.e.
Jiti Gao, Pipat Wongsaart
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Advanced Science, EarlyView.ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung +19 more
wiley +1 more source
Restricted Gompertz-Type Diffusion Processes with Periodic Regulation Functions
Mathematics, 2019 We consider two different time-inhomogeneous diffusion processes useful to model the evolution of a population in a random environment. The first is a Gompertz-type diffusion process with time-dependent growth intensity, carrying capacity and noise ...
Virginia Giorno, Amelia G. Nobile
doaj +1 more source
Density conditions in Fréchet and (DF)-spaces
Revista Matemática Complutense, 1989 Summary: We survey our main results on the density condition for Fréchet spaces and on the dual density conditions for (DF)-spaces as well as some recent developments. At the end of section 1., we include a new result on the projective tensor product of two Fréchet spaces.
Bierstedt, Klaus Dieter, Bonet, José
openaire +3 more sources
PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility
Advanced Science, EarlyView.PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao +7 more
wiley +1 more source
A density condition for interpolation on the Heisenberg group
Rocky Mountain Journal of Mathematics, 2012 Let $N$ be the Heisenberg group. We consider left-invariant multiplicity free subspaces of $L^2(N)$. We prove a necessary and sufficient density condition in order that such subspaces possess the interpolation property with respect to a class of discrete subsets of $N$ that includes the integer lattice.
Currey, Bradley, Mayeli, Azita
openaire +4 more sources
A Consistent Test for Multivariate Conditional Distributions [PDF]
We propose a new test for a multivariate parametric conditional distribution of a vector of variables yt given a conditional vector xt. The proposed test is shown to have an asymptotic normal distribution under the null hypothesis, while being consistent
Greg Tkacz, Fuchun Li
core