Results 71 to 80 of about 3,051,269 (303)

Grtp1 Safeguards Against Paternal Reproductive Aging and Intergenerational Behavioral Deficits by Preserving Redox Homeostasis

open access: yesAdvanced Science, EarlyView.
This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu   +23 more
wiley   +1 more source

Nonparametric checks for count data models: an application to demand for health care in Spain [PDF]

open access: yes, 1997
This paper presents model specification checking procedures for count data regression models which are consistent in the direction of nonparametric alternatives.
Delgado, Miguel A., Álvarez, Begoña
core   +1 more source

A New Extension of Thinning-Based Integer-Valued Autoregressive Models for Count Data

open access: yesEntropy, 2020
The thinning operators play an important role in the analysis of integer-valued autoregressive models, and the most widely used is the binomial thinning.
Zhengwei Liu, Fukang Zhu
doaj   +1 more source

The element-wise weighted total least squares problem

open access: yes, 2006
A new technique for parameter estimation is considered in a linear measurement error model AX approx B, A = A0 + tilde A, B = B0 + tilde B, with row-wise independent and non-identically distributed measurement errors tilde A, tilde B.
Premoli, P.   +3 more
core  

Chemotherapy‐Activated GSK3β‐DNMT1 Signaling Upregulates CD47 to Evade Macrophage Phagocytosis and Drive Temozolomide Resistance in Glioblastoma

open access: yesAdvanced Science, EarlyView.
Temozolomide treatment activates GSK3β, driving DNMT1 phosphorylation, destabilization, and CD47 promoter hypomethylation in glioblastoma. This epigenetic shift upregulates CD47, enabling TMZ‐treated GBM cells to evade macrophage phagocytosis, survive chemotherapy, and acquire resistance.
Jie Li   +11 more
wiley   +1 more source

Financial digitization infrastructure, educational expenditure and sustainable development outcomes: Evidence from a multi-country panel in sub-Saharan Africa [PDF]

open access: yesAccounting
This paper examines the relationship between digital payment infrastructure (DPI), education spending, and government performance to produce sustainable development outcomes in a Sub-Saharan Africa (SSA). On panel data of Kenya, Nigeria, South
Jude Igyo Ali, Patricia Lindelwa Makoni
doaj   +1 more source

MXene‐Based Room‐Temperature NO2 Gas Sensors: A Meta‐Analysis

open access: yesAdvanced Science, EarlyView.
This study presents the first comprehensive meta‐analysis of MXene‐based NO2 sensors, decoding 32 study characteristics across 61 peer‐reviewed studies. By isolating materials chemistry as the primary performance driver over device‐level parameters, the authors establish a methodological blueprint and a predictive structure–function map to accelerate ...
Alexander Khort   +3 more
wiley   +1 more source

Local Regularization Assisted Orthogonal Least Squares Regression

open access: yes, 2006
A locally regularized orthogonal least squares (LROLS) algorithm is proposed for constructing parsimonious or sparse regression models that generalize well.
Chen, S.
core   +1 more source

On the complex least squares problem with constrained phase [PDF]

open access: yes, 2011
The problem of solving approximately in the least squares sense an overdetermined linear system of equations with complex valued coefficients is considered, where the elements of the solution vector are constrained to have the same phase.
Markovsky, Ivan, Ivan Markovsky
core   +2 more sources

Least squares fitting the three-parameter inverse Weibull density [PDF]

open access: yes, 2010
The inverse Weibull model was developed by Erto [10]. In practice, the unknown parameters of the appropriate inverse Weibull density are not known and must be estimated from a random sample.
Marušić, Miljenko   +2 more
core   +1 more source

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