Results 81 to 90 of about 3,051,269 (303)

A new stabilized least-squares imaging condition

Journal of Geophysics and Engineering, 2009
The classical deconvolution imaging condition consists of dividing the upgoing wave field by the downgoing wave field and summing over all frequencies and sources. The least-squares imaging condition consists of summing the cross-correlation of the upgoing and downgoing wave fields over all frequencies and sources, and dividing the result by the total ...
Flor A Vivas, Reynam C Pestana, Bjørn Ursin   +2 more
openaire   +1 more source

Overview of total least squares methods

, 2007
We review the development and extensions of the classical total least squares method and describe algorithms for its generalization to weighted and structured approximation problems.
Markovsky, Ivan, Van Huffel, Sabine
core  

Least-squares methods for identifying biochemical regulatory networks from noisy measurements [PDF]

, 2007
<b>Background</b>: We consider the problem of identifying the dynamic interactions in biochemical networks from noisy experimental data.
Postlethwaite, I., Kwang-Hyun Cho, Kim, Jongrae, Heslop-Harrison, P., Heslop-Harrison, Pat, Postlethwaite, I, Bates, D.G., Cho, Kwang-Hyun, Postlethwaite, Ian, Declan G Bates, Bates, DG, Kim, J, Kim, J., Ian Postlethwaite, Cho, K-H., Jongrae Kim, Pat Heslop-Harrison, Bates, Declan, Heslop-Harrison, P, Postlethwaite Ian, Cho Kwang-Hyun, Bates Declan G, Kim Jongrae, Heslop-Harrison Pat   +23 more
core   +1 more source

Single‐Molecule Imaging of Endogenous RNA Using a Miniaturized and Circularly Permuted CRISPR‐Cas13 Degron‐Masking System CDegSR

Advanced Science, EarlyView.
CDegSR, a new tool for imaging RNA at single molecule level in living cells was developed by researchers. Background noise was eliminated by protein engineering and making it degrade when not bound to its target. This allowed individual RNA molecules to be clearly imaged and tracked.
Shipeng Shao, Hongchen Zhang
wiley   +1 more source

Reweighted Least Trimmed Squares: An Alternative to One-Step Estimators [PDF]

A new class of robust regression estimators is proposed that forms an alternative to traditional robust one-step estimators and that achieves the √n rate of convergence irrespective of the initial estimator under a wide range of distributional ...
Cizek, P.
core  

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

Advanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale, Barbara Vona, Richard J. Goodyear, Richard T. Osgood, Jun Shen, Sami S. Amr, Karen Mojica, Michaela A. H. Hofrichter, Jörg Schröder, Sophie Flandin, Paul Gratias, Ricardo Vera‐Monroy, Katherine Callahan, Kerry L. Gudlewski, Rolen Quadros, Masato Ohtsuka, JoAnn McGee, Edward J. Walsh, Cynthia C. Morton, Thomas Haaf, Channabasavaiah Gurumurthy, James E. Saunders, Guy P. Richardson, Artur A. Indzhykulian   +23 more
wiley   +1 more source

Consistent least squares fitting of ellipsoids

, 2004
A parameter estimation problem for ellipsoid fitting in the presence of measurement errors is considered. The ordinary least squares estimator is inconsistent, and due to the nonlinearity of the model, the orthogonal regression estimator is inconsistent ...
Van Huffel, S., Kukush, A., Markovsky, I.   +2 more
core   +1 more source

Solution of the Least Squares Method problem of pairwise comparison matrices [PDF]

, 2008
Pairwise comparison matrix, Least squares approximation, Polynomial system, Homotopy method, Incomplete pairwise comparison matrix,
Bozóki, Sándor
core   +1 more source

SIRT7‐Mediated H2BK120 Succinylation Drives Aberrant Mitophagy in Sepsis‐Associated Cognitive Dysfunction

Advanced Science, EarlyView.
Sepsis triggers hippocampal SIRT7 loss, promoting histone H2B succinylation and activation of the PD‐1/PD‐L1–PINK1 axis. This metabolic‐epigenetic cascade drives aberrant mitophagy and neuronal injury, ultimately causing cognitive deficits. Targeting SIRT7‐dependent succinylation offers a potential strategy to protect brain function during sepsis ...
Na Meng, Jiateng Zhou, Xiaoyu Guo, Ting Hong, Xuelian Li, Xingyu Wei, Chanhua Zhang, Xixue Zhang, Songbin Liu, Yulin Zhang, Liangfang Yao, Lina Huang, Weidong Gu   +12 more
wiley   +1 more source

A Time-Varying Mixture Integer-Valued Threshold Autoregressive Process Driven by Explanatory Variables

Entropy
In this paper, a time-varying first-order mixture integer-valued threshold autoregressive process driven by explanatory variables is introduced. The basic probabilistic and statistical properties of this model are studied in depth.
Danshu Sheng, Dehui Wang, Jie Zhang, Xinyang Wang, Yiran Zhai   +4 more
doaj   +1 more source