Results 81 to 90 of about 6,175 (306)

Hypomyelination in autism-associated neuroligin-3 mutant mice impairs parvalbumin interneuron excitability, gamma oscillations, and sensory discrimination

Nature Communications
Whether and how myelin plasticity, an emerging new form of brain plasticity, is involved in autism spectrum disorder (ASD) remains unknown. Here, we identify deficits in oligodendrocyte (OL) generation and myelination in the barrel cortex (BC) of the ...
Yongxiang He, Jiong Li, Wei Zheng, Junhong Liu, Zhaojun Dong, Lu Yang, Shuting Tang, Yanping Zou, Tianyu Gao, Yuqian Yang, Zhenpeng Mo, Shuming Wang, Yuehua He, Changyong Tang, Jianhong Luo, Jingwei Zhao, Guoqing Guo, Huiliang Li, Lin Xiao   +18 more
doaj   +1 more source

Mesenchymal Circadian Clock Regulates TMJ Osteochondral Homeostasis During Aging

International Dental Journal
Aim or purpose: The prevalence of temporomandibular joint osteoarthritis (TMJ-OA) increases with aging. However, research focused on age-related mechanisms is rare.
Wenzhen Gao, Chenchen Zhou, Sa Cha, Qing Zhao   +3 more
doaj   +1 more source

Explaining the high skill of reservoir computing methods in El Niño prediction [PDF]

Nonlinear Processes in Geophysics
Accurate prediction of the extreme phases of the El Niño–Southern Oscillation (ENSO) is important to mitigate the socioeconomic impacts of this phenomenon. It has long been thought that prediction skill was limited to a 6-month lead time.
F. Guardamagna, F. Guardamagna, C. Wieners, C. Wieners, H. A. Dijkstra, H. A. Dijkstra   +5 more
doaj   +1 more source

Physics‐Grounded Probabilistic Bits for Hardware‐Efficient Intelligent Inference and Optimization

Advanced Intelligent Systems, EarlyView.
Si–SiNx interface traps are harnessed as a complementary metal–oxide–semiconductor‐compatible source of controllable randomness for probabilistic bits. Pulse‐width‐programmed stochastic capture converts nanoscale defect dynamics into Boltzmann‐consistent binary outputs, while a physics‐based Simulation Program with Integrated Circuit Emphasis model ...
Dokyoung Lee, Jun‐Young Park, Joon‐Kyu Han, Sungho Kim   +3 more
wiley   +1 more source

Quantum Phenomena in Molecular and Biological Systems: A Decoherence‐Based Decision Framework With Falsifiable Predictions and a Failure‐Mode Taxonomy

Advanced Physics Research, EarlyView.
A physics‐grounded framework based on decoherence timescales (τ_dec vs τ_func), Markovian validity, and falsifiability criteria is applied across molecular systems to distinguish where quantum effects are necessary, marginal, or irrelevant. The analysis integrates quantum chemistry, biological quantum mechanisms, and quantum computing under a unified ...
Sarfaraz K. Niazi
wiley   +1 more source

Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease

Arthritis &Rheumatology, EarlyView.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel, Manigandan Venkatesan, Rahul S. Jasrotia, Yuyang Sun, Viviane Nascimento da Conceicao, Neelanjan Vishnu, Shankara N. Varadarajan, Venugopal R. Bovilla, Rajender K. Motiani, Shobhan Gaddameedhi, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh   +12 more
wiley   +1 more source

Oscillation and nonoscillation of solutions to even order self-adjoint differential equations

Electronic Journal of Differential Equations, 2003
We establish oscillation and nonoscilation criteria for the linear differential equation $$ (-1)^nig(t^alpha y^{(n)}ig)^{(n)}- frac{gamma_{n,alpha}}{t^{2n-alpha}}y=q(t)y,quad alpha otin {1, 3, dots , 2n-1}, $$ where $$ gamma_{n,alpha}=frac{1}{4^n}prod_ ...
Ondrej Dosly, Simona Fisnarova
doaj  

Weather forecasting for weather derivatives : [revised version: January 2, 2004]

, 2004
We take a simple time-series approach to modeling and forecasting daily average temperature in U.S. cities, and we inquire systematically as to whether it may prove useful from the vantage point of participants in the weather derivatives market.
Diebold, Francis X., Campbell, Sean D.
core  

Mimic, target, and adapt: Cell membrane‐coated nanoplatforms for precision and immune‐guided cancer treatment

BMEMat, EarlyView.
This Perspective explores the emerging landscape of cell membrane‐coated nanoparticles (CM‐NPs) as intelligent, immune‐compatible platforms for cancer therapy. Highlighting design strategies, translational challenges, and competitive positioning, it outlines how integrating biomimetic targeting with advanced analytical and manufacturing tools could ...
A. K. M. M. Alam, Xiaojun Cai, Malik Ihsan Ullah Khan, Robert Musiol, Quazi T. H. Shubhra   +4 more
wiley   +1 more source

Three CNGC Family Members, CNGC5, CNGC6, and CNGC9, Are Required for Constitutive Growth of Arabidopsis Root Hairs as Ca2+-Permeable Channels

Plant Communications, 2020
The genetic identities of Ca2+ channels in root hair (RH) tips essential for constitutive RH growth have remained elusive for decades. Here, we report the identification and characterization of three cyclic nucleotide-gated channel (CNGC) family members,
Yan-Qiu Tan, Yang Yang, An Zhang, Cui-Fang Fei, Li-Li Gu, Shu-Jing Sun, Wei Xu, Lingling Wang, Hongtao Liu, Yong-Fei Wang   +9 more
doaj   +1 more source