Results 121 to 130 of about 1,549,528 (298)

GM‐CSF Promotes Neutrophil PD‐L1 Expression Through the VEGFR‐2/STAT6/CSF2 Signaling Axis in Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu   +13 more
wiley   +1 more source

Mortgage Terminations: The Role of Conditional Volatility [PDF]

open access: yes
This article is the winner of the Real Estate Finance manuscript prize (sponsored by Fannie Mae Foundation) presented at the 2001 American Real Estate Society Annual Meeting.
David M. Harrison   +2 more
core  

Reconditioning the conditional [Recondicionando o condicional]

open access: yesPrincípios, 2016
Many authors have hoped to understand the indicative conditional construction in everyday language by means of what are usually called conditional probabilities. Other authors have hoped to make sense of conditional probabilities in terms of the absolute
David Miller
doaj   +2 more sources

TSTScope Unifies Single‐Cell Multi‐Omics to Identify Functional T Cell States Predictive of Immunotherapy Response

open access: yesAdvanced Science, EarlyView.
TSTScope is an interpretable AI framework that integrates single‐cell transcriptomes with TCR information through curated gene‐program constraints. By linking receptor context to functional T cell states, it reveals response‐associated tumor‐specific T cell programs in lung cancer immunotherapy cohorts and defines an MPR score associated with ...
Shiwei Cao   +8 more
wiley   +1 more source

Conditional and Dynamic Convex Risk Measures [PDF]

open access: yes
We extend the definition of a convex risk measure to a conditional framework where additional information is available. We characterize these risk measures through the associated acceptance sets and prove a representation result in terms of conditional ...
Kai Detlefsen, Giacomo Scandolo
core  

Dipolar Coupling Errors in Nuclear Spin Qubits

open access: yesAdvanced Science, EarlyView.
Multi‐nuclear spin registers of phosphorus‐atom qubits in silicon have demonstrated 99.99% single and >$>$99.9% two qubit gate fidelities. Despite nanometer separation, read‐out fidelities between individual nuclear spins within the register are not identical.
I. D. Thorvaldson   +15 more
wiley   +1 more source

Conditional density estimation: an application to the Ecuadorian manufacturing sector [PDF]

open access: yes
This note applies conditional density estimation as a visual method to present results. The proposed method is illustrated by application to a firm-level manufacturing data set from Ecuador in 2002.Density ...
Kim Huynh, David Jacho-Chavez
core  

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