Results 31 to 40 of about 3,593 (265)

Intercategorical interactions in non-prototypical taxis constructions of the German language

open access: yesНеофилология, 2023
The subject of the research is the description of intercategorial interactions in nonprototypical taxis constructions of the German language. The aim of the work is to analyze the intercategorical connections of taxis with the semantic categories of ...
I. V. Archipova
doaj   +1 more source

Recent Changes of IMF Conditionality and Its Effects on Social Spending [PDF]

open access: yesRevista de Management Comparat International, 2015
The IMF programs have been long criticized for having adverse effects on social spending. Yet, on the onset of the global financial crisis, it has undergone major changes aiming at streamlining its conditionality by introducing novel arrangements and ...
Gurgen OHANYAN
doaj  

The Rule of Law, the Force of Law and the Power of Money in the EU

open access: yesCroatian Yearbook of European Law and Policy, 2019
This paper discusses the strengths and weaknesses of the rule of law conditionality contained in the Proposal for a Regulation on the protection of the Union’s budget in case of generalised deficiencies as regards the rule of law in the Member States ...
Iris Goldner Lang
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

An Analysis of IMF Conditionality [PDF]

open access: yes, 2003
Conditionality is the most controversial aspect of the IMF`s policies. It has been said to be intrusive and coercive and considered to disregard effects on growth, employment and income distribution. In the 1990s, following a sharp increase in the number of conditions required by programs, Fund conditionality became increasingly ineffective.
openaire   +5 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

EU External Relations from Non-Intervention to Political Conditionality [PDF]

open access: yesCentral European Journal of International & Security Studies, 2011
The international system developed after the Peace of Westphalia placed at its core the idea that nation-states are equal units that cannot intervene in the internal affairs of other states, an idea which ultimately led to the conclusion that ...
Dan Lazea
doaj  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

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